Epigenetic lifestyle of Epstein-Barr virus

A Buschle, W Hammerschmidt - Seminars in immunopathology, 2020 - Springer
Epstein-Barr virus (EBV) is a model of herpesvirus latency and epigenetic changes. The
virus preferentially infects human B-lymphocytes (and also other cell types) but does not turn …

Mechanisms of B-cell oncogenesis induced by Epstein-Barr virus

A Saha, ES Robertson - Journal of Virology, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects
the majority of the world population. Under immunocompromised conditions, EBV can …

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

P Mrozek-Gorska, A Buschle, D Pich… - Proceedings of the …, 2019 - National Acad Sciences
Epstein–Barr virus (EBV) is a human tumor virus and a model of herpesviral latency. The
virus efficiently infects resting human B lymphocytes and induces their continuous …

N (6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay

TL Xia, X Li, X Wang, YJ Zhu, H Zhang, W Cheng… - EMBO …, 2021 - embopress.org
Abstract N 6‐methyladenosine (m6A) modification of mRNA mediates diverse cellular and
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …

Keeping it quiet: chromatin control of gammaherpesvirus latency

PM Lieberman - Nature reviews Microbiology, 2013 - nature.com
Abstract The human gammaherpesviruses Epstein–Barr virus (EBV) and Kaposi's sarcoma-
associated herpesvirus (KSHV) establish long-term latent infections associated with diverse …

Epigenetic regulation of EBV persistence and oncogenesis

I Tempera, PM Lieberman - Seminars in cancer biology, 2014 - Elsevier
Epigenetic mechanisms play a fundamental role in generating diverse and heritable
patterns of viral and cellular gene expression. Epstein–Barr virus (EBV) can adopt a variety …

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

WKJ Lam, P Jiang, KCA Chan, W Peng… - Nature …, 2019 - nature.com
Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies.
Currently, it is not known whether patients with different EBV-associated diseases have …

The roles of DNA methylation on the promotor of the Epstein–Barr virus (EBV) gene and the genome in patients with EBV-associated diseases

L Zhang, R Wang, Z Xie - Applied Microbiology and Biotechnology, 2022 - Springer
Epstein–Barr virus (EBV) is an oncogenic virus that is closely associated with several
malignant and lymphoproliferative diseases. Studies have shown that the typical …

Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis

Y Shi, SL Peng, LF Yang, X Chen, YG Tao… - Chinese journal of …, 2016 - Springer
Viral infections contribute to approximately 12% of cancers worldwide, with the vast majority
occurring in developing countries and areas. Two DNA viruses, Epstein-Barr virus (EBV) …

Genomic assays for Epstein–Barr virus-positive gastric adenocarcinoma

ML Gulley - Experimental & molecular medicine, 2015 - nature.com
A small set of gastric adenocarcinomas (9%) harbor Epstein–Barr virus (EBV) DNA within
malignant cells, and the virus is not an innocent bystander but rather is intimately linked to …