SLC26 anion transporters

ER Geertsma, D Oliver - Anion Channels and Transporters, 2023 - Springer
Abstract Solute carrier family 26 (SLC26) is a family of functionally diverse anion
transporters found in all kingdoms of life. Anions transported by SLC26 proteins include …

[HTML][HTML] Functional studies of deafness-associated pendrin and prestin variants

S Takahashi, T Kojima, K Wasano… - International Journal of …, 2024 - mdpi.com
Pendrin and prestin are evolutionary-conserved membrane proteins that are essential for
normal hearing. Dysfunction of these proteins results in hearing loss in humans, and …

[HTML][HTML] The molecular principles underlying diverse functions of the SLC26 family of proteins

S Takahashi, K Homma - Journal of Biological Chemistry, 2024 - ASBMB
Mammalian SLC26 proteins are membrane-based anion transporters that belong to the
large SLC26/SulP family, and many of their variants are associated with hereditary diseases …

Single cell transcriptomic analysis of the canine duodenum in chronic inflammatory enteropathy and health

AC Manchester, DT Ammons, MR Lappin… - Frontiers in …, 2024 - frontiersin.org
Chronic inflammatory enteropathy (CIE) is a common condition in dogs causing recurrent or
persistent gastrointestinal clinical signs. Pathogenesis is thought to involve intestinal …

Oligomerization and cellular localization of SLC26A11

S Bungert-Pluemke, RE Guzman, C Fahlke - bioRxiv, 2024 - biorxiv.org
The solute carrier family 26 (SLC26) encompasses multifunctional anion exchangers in all
kingdoms of life. SLC26 proteins are known to assemble as dimers, and co-expression of …

[HTML][HTML] Mechanism of anion exchange and small-molecule inhibition of pendrin

L Wang, A Hoang, E Gil-Iturbe, A Laganowsky… - Nature …, 2024 - nature.com
Abstract Pendrin (SLC26A4) is an anion exchanger that mediates bicarbonate (HCO3−)
exchange for chloride (Cl−) and is crucial for maintaining pH and salt homeostasis in the …