The hypothalamic-pituitary-adrenal axis in pregnancy: challenges in disease detection and treatment

JR Lindsay, LK Nieman - Endocrine reviews, 2005 - academic.oup.com
Pregnancy dramatically affects the hypothalamic-pituitary-adrenal axis leading to increased
circulating cortisol and ACTH levels during gestation, reaching values in the range seen in …

Cushing's syndrome during pregnancy: personal experience and review of the literature

JR Lindsay, J Jonklaas, EH Oldfield… - The Journal of Clinical …, 2005 - academic.oup.com
Cushing's syndrome (CS) occurs rarely during pregnancy. We investigated and treated four
patients with pituitary-dependent Cushing's syndrome during pregnancy over a 15-yr period …

ESE Clinical Practice Guideline on functioning and nonfunctioning pituitary adenomas in pregnancy

A Luger, LHA Broersen, NR Biermasz… - European journal of …, 2021 - academic.oup.com
Pregnancies are rare in women with pituitary adenomas, which may relate to hormone
excess from secretory subtypes such as prolactinomas or corticotroph adenomas …

The diagnosis and management of Cushing's syndrome in pregnancy

R Hamblin, A Coulden, A Fountas… - Journal of …, 2022 - Wiley Online Library
Endogenous Cushing's syndrome (CS) is rarely encountered during pregnancy. Clinical and
biochemical changes in healthy pregnancy overlap with those seen in pregnancy …

Clinical and biochemical characteristics of adrenocorticotropin-secreting macroadenomas

YS Woo, AM Isidori, WZ Wat, GA Kaltsas… - The Journal of …, 2005 - academic.oup.com
Context: Cushing's disease as a result of a pituitary macroadenoma is an uncommon cause
of Cushing's syndrome, and reports in the published literature are few and of limited size …

Management of pituitary tumors in pregnancy

MD Bronstein, DB Paraiba, RS Jallad - Nature Reviews Endocrinology, 2011 - nature.com
Pituitary tumors, usually adenomas, account for about 10–15% of all intracranial tumors.
Their treatment, which includes surgery, medicine or radiotherapy, either isolated or in …

Pituitary tumors and pregnancy

ME Molitch - Growth Hormone & IGF Research, 2003 - Elsevier
Tumors vary in how they affect pregnancy depending upon the hormone secreted. Some
hormone oversecretion syndromes must be controlled to allow pregnancy to proceed …

Pituitary disorders during pregnancy

ME Molitch - Endocrinology and Metabolism Clinics, 2006 - endo.theclinics.com
Pituitary adenomas are common in women, constituting 5.7% of intracranial (malignant and
nonmalignant) neoplasms, with an age-adjusted incidence rate of 0.82 cases/100,000 …

Corticosteroids and pregnancy

PJ Trainer - Seminars in Reproductive Medicine, 2002 - thieme-connect.com
Pregnancy results in major changes in the hypothalamo-pituitary-adrenal (HPA) axis, which
in turn influence fetal growth and the timing of labor. From the beginning of the second …

Adrenal disease in pregnancy

O Lekarev, MI New - Best Practice & Research Clinical Endocrinology & …, 2011 - Elsevier
Adrenal disorders in pregnancy are relatively rare, yet can lead to significant maternal and
fetal morbidity. Making a diagnosis is challenging as pregnancy may alter the manifestation …