[HTML][HTML] Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease

B Li, Y Wang, X Jiang, H Du, Y Shi, M Xiu, Y Liu… - Biomedicine & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a special chronic intestinal inflammatory disease, which
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …

Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the …

M Ghasemi-Dehnoo, H Amini-Khoei, Z Lorigooini… - …, 2023 - Springer
Introduction Ulcerative colitis is a chronic inflammation of the colon. However, the common
treatment for it is accompanied by many complications. Therefore, the present study was …

Anti-amnesic and neuroprotective potential of Genistein against Alzheimer's Disease

NK Singh, N Verma, JK Gupta, J Raghav - Revista Brasileira de …, 2024 - Springer
Alzheimer's disease, the most prevalent neurodegenerative disorder, is characterized by
language deficits, impairment of problem-solving ability, loss of learning abilities, and …

Genistein ameliorated experimentally induced gastric ulcer in rats via inhibiting gastric tissues fibrosis by modulating Wnt/β-catenin/TGF-β/PKB pathway

HM Hassan, NM Alatawi, A Bagalagel, R Diri… - Redox …, 2023 - Taylor & Francis
Objectives Gastric ulcer (GU) is a prevalent chronic digestive disease affecting about 10% of
the world's population leading to gastrointestinal perforation and bleeding. Genistein is a …

[HTML][HTML] Antitumor activity of luteolin against Ehrlich solid carcinoma in rats via blocking Wnt/β-Catenin/SMAD4 pathway

H Aljohani, AE Khodier, MM Al-Gayyar - Cureus, 2023 - ncbi.nlm.nih.gov
Background Ehrlich solid carcinoma (ESC) is characterized by rapid proliferation and a short
survival time. Because Ehrlich ascites carcinoma (EAC) resembles human cancer cells …

[HTML][HTML] Antitumor activity of ligustilide against Ehrlich solid carcinoma in rats via inhibition of proliferation and activation of autophagy

AF Alshehri, AE Khodier, MM Al-Gayyar - Cureus, 2023 - ncbi.nlm.nih.gov
Background Cancer is the second-leading cause of death worldwide. According to a 2018
WHO report, 9.6 million deaths occurred globally due to cancer. Ehrlich carcinoma is …

[HTML][HTML] Antitumor activity of ferulic acid against Ehrlich solid carcinoma in rats via affecting hypoxia, oxidative stress and cell proliferation

MA Alghamdi, TA Khalifah, HS Alhawati, M Ruzayq… - Cureus, 2023 - ncbi.nlm.nih.gov
Background Ferulic acid is a natural compound commonly found in fruits and vegetables like
tomatoes, sweet corn, rice bran, and dong quai. It has various beneficial effects on the body …

[HTML][HTML] Arctiin inhibits inflammation, fibrosis, and tumor cell migration in rats with Ehrlich solid carcinoma

BM Alfair, AA Jabarti, SS Albalawi, AE Khodir… - Cureus, 2023 - ncbi.nlm.nih.gov
Background and objectives: ESC or Ehrlich solid carcinoma is a type of tumor originating
from a spontaneous mammary adenocarcinoma in mice. It is a highly aggressive and fast …

[HTML][HTML] Garcinol-attenuated gastric ulcer (GU) experimentally induced in rats via affecting inflammation, cell proliferation, and DNA polymerization

YF Alatawi, MA Alhablani, FA Al-Rashidi, WS Khubrani… - Cureus, 2023 - ncbi.nlm.nih.gov
Background: Gastric ulcer (GU) is one of the most critical gastrointestinal tract disorders.
Garcinol is a polyisoprenylated benzophenone in Garcinia fruit with antioxidant and anti …

[HTML][HTML] Role of arctiin in fibrosis and apoptosis in experimentally induced hepatocellular carcinoma in rats

SA Alshehri, WA Almarwani, AZ Albalawi, SM Al-Atwi… - Cureus, 2024 - ncbi.nlm.nih.gov
Methods Rats were induced with HCC by administering thioacetamide. Arctiin was orally
administered to some rats twice a week for 16 weeks at a dose of 30 mg/kg. The liver …