Mitochondria are highly dynamic organelles undergoing cycles of fusion and fission to
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …

Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

In neurodegenerative diseases, debris of dead neurons are thought to trigger glia-mediated
neuroinflammation, thus increasing neuronal death. Here we show that the expression of …

Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

Mitochondria, the membrane-bound cell organelles that supply most of the energy needed
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …

CD8+ T cells play a central role in anti-tumor immunity. Naïve CD8+ T cells are active upon
tumor antigen stimulation, and then differentiate into functional cells and migrate towards the …

Mitochondrial dysfunction is a key contributor to septic cardiomyopathy. Although recent
literature implicates dynamin related protein 1 (Drp1) and its mitochondrial adaptor fission 1 …

Ischemic stroke is one of the leading causes of death and also a major cause of adult
disability worldwide. Revascularization via reperfusion therapy is currently a standard …

Mitochondrial dysfunction and cell senescence are hallmarks of aging and are closely
interconnected. Mitochondrial dysfunction, operationally defined as a decreased respiratory …

Neurons are highly polarised, complex and incredibly energy intensive cells, and their
demand for ATP during neuronal transmission is primarily met by oxidative phosphorylation …