Tuberculosis in the elderly

P Caraux-Paz, S Diamantis, B de Wazières… - Journal of Clinical …, 2021 - mdpi.com
The tuberculosis (TB) epidemic is most prevalent in the elderly, and there is a progressive
increase in the notification rate with age. Most cases of TB in the elderly are linked to the …

[HTML][HTML] COVID-19 and tuberculosis: the double whammy of respiratory pathogens

M Shariq, JA Sheikh, N Quadir… - European …, 2022 - Eur Respiratory Soc
Prior to coronavirus disease 2019 (COVID-19), tuberculosis (TB) was the worst killer among
infectious diseases. The union of these two obnoxious respiratory diseases can be …

Corticosteroids for COVID-19 therapy: potential implications on tuberculosis

R Gopalaswamy, S Subbian - International journal of molecular sciences, 2021 - mdpi.com
On 11 March 2020, the World Health Organization announced the Corona Virus Disease-
2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID …

Formation and maturation of the phagosome: a key mechanism in innate immunity against intracellular bacterial infection

HJ Lee, Y Woo, TW Hahn, YM Jung, YJ Jung - Microorganisms, 2020 - mdpi.com
Phagocytosis is an essential mechanism in innate immune defense, and in maintaining
homeostasis to eliminate apoptotic cells or microbes, such as Mycobacterium tuberculosis …

Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections

S Subramaniam, P Joyce, N Thomas… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Chemical Synthesis of Cell Wall Constituents of Mycobacterium tuberculosis

M Holzheimer, J Buter, AJ Minnaard - Chemical reviews, 2021 - ACS Publications
The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an
extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans. These …

Systemic diseases and the cornea

R Shah, C Amador, K Tormanen, S Ghiam… - Experimental eye …, 2021 - Elsevier
There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

The relationship between vitamin D and infections including COVID-19: any hopes?

R Taha, S Abureesh, S Alghamdi… - … journal of general …, 2021 - Taylor & Francis
Vitamin D is proposed to have a potential role in the pathogenicity, clinical presentation,
prognosis, complications, and treatment of several diseases. In addition to its well-known …

T cell immunity to bacterial pathogens: mechanisms of immune control and bacterial evasion

FR Shepherd, JE McLaren - International journal of molecular sciences, 2020 - mdpi.com
The human body frequently encounters harmful bacterial pathogens and employs immune
defense mechanisms designed to counteract such pathogenic assault. In the adaptive …

Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection

A Nisa, FC Kipper, D Panigrahy… - … of Physiology-Cell …, 2022 - journals.physiology.org
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …