Hydrocephalus in children

KT Kahle, AV Kulkarni, DD Limbrick, BC Warf - The lancet, 2016 - thelancet.com
Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …

Spina bifida

AJ Copp, NS Adzick, LS Chitty, JM Fletcher… - Nature reviews Disease …, 2015 - nature.com
Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord
involvement. The most clinically significant subtype is myelomeningocele (open spina …

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

JK Karimy, BC Reeves, E Damisah, PQ Duy… - Nature Reviews …, 2020 - nature.com
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement

N Tulipan, JC Wellons, EA Thom, N Gupta… - Journal of …, 2015 - thejns.org
OBJECT The Management of Myelomeningocele Study (MOMS) was a multicenter
randomized trial comparing the safety and efficacy of prenatal and postnatal closure of …

Global neurosurgery: innovators, strategies, and the way forward: JNSPG 75th Anniversary Invited Review Article

MM Haglund, AT Fuller - Journal of neurosurgery, 2019 - thejns.org
Around the world today, low-and middle-income countries (LMICs) have not benefited from
advancements in neurosurgery; most have minimal or even no neurosurgical capacity in …

Endoscopic third ventriculostomy in children: prospective, multicenter results from the Hydrocephalus Clinical Research Network

AV Kulkarni, J Riva-Cambrin, R Holubkov… - Journal of …, 2016 - thejns.org
OBJECTIVE Endoscopic third ventriculostomy (ETV) is now established as a viable
treatment option for a subgroup of children with hydrocephalus. Here, the authors report …

Endoscopic third ventriculostomy and choroid plexus cauterization in infant hydrocephalus: a prospective study by the Hydrocephalus Clinical Research Network

AV Kulkarni, J Riva-Cambrin, CJ Rozzelle… - Journal of …, 2018 - thejns.org
OBJECTIVE High-quality data comparing endoscopic third ventriculostomy (ETV) with
choroid plexus cauterization (CPC) to shunt and ETV alone in North America are greatly …

Pediatric hydrocephalus: current state of diagnosis and treatment

Z Wright, TW Larrew, R Eskandari - Pediatrics in review, 2016 - publications.aap.org
Hydrocephalus is a neurologic condition that requires lifelong vigilance by various health
care professionals. Nonsurgical clinicians treating children with hydrocephalus, with or …

First 60 fetal in-utero myelomeningocele repairs at Saint Louis Fetal Care Institute in the post-MOMS trial era: hydrocephalus treatment outcomes (endoscopic third …

SK Elbabaa, AM Gildehaus, MJ Pierson, JA Albers… - Child's Nervous …, 2017 - Springer
Introduction The published results of the Management of Myelomeningocele Study (MOMS)
trial in 2011 showed improved outcomes (reduced need for shunting, decreased incidence …

Cerebrospinal fluid hypersecretion in pediatric hydrocephalus

JK Karimy, D Duran, JK Hu, C Gavankar… - Neurosurgical …, 2016 - thejns.org
Hydrocephalus, despite its heterogeneous causes, is ultimately a disease of disordered CSF
homeostasis that results in pathological expansion of the cerebral ventricles. Our current …