Tachykinin NK 2 receptors are distributed in periphery, in the smooth muscle of the
respiratory, gastrointestinal, genitourinary tract, and within the brain. Substance P (SP) …

In the present study, we investigated the role of acetylcholine, tachykinins and kinins in the
bronchoconstriction induced by cold air inhalation. Cold air was delivered to anaesthetised …

Both tachykinins and leukotrienes (LTs) have been demonstrated to be the mediators for
hyperpnea-induced bronchoconstriction (HIB) of guinea pigs. We tested the hypothesis that …

This study was designed to test the hypotheses that (1) neurokinin (NK) receptor activity
modulates hyperventilation-induced bronchoconstriction (HIB) in canine peripheral airways …

Yang, XX, WS Powell, M. Hojo, and JG Martin. Hyperpnea-induced bronchoconstriction is
dependent on tachykinin-induced cysteinyl leukotriene synthesis. J. Appl. Physiol. 82 (2) …

Tachykinins are neuropeptides which regulate various biological responses, some of which
are potentially important in the pathogenesis of pulmonary diseases such as asthma …

Inhalation of cold air in guinea pigs increases total pulmonary resistance (Rl), an effect that
is mediated by kinins and tachykinins. Bronchoconstriction induced by bradykinin (BK) …

CO bicarbonate 2 produced component by the working of lactate muscles, isocapnic
because buffering. additional At higher CO2 is work generated loads, a from further the …

Neurokinin A (NKA) induces bronchoconstriction mediated by tachykinin NK2 receptors in
animals and humans, and may be increased in asthma. Because β2-adrenoceptor agonists …

Neurokinin A is not only a potent bronchoconstrictor, but also has immuno-modulatory
effects in animals and man, mediated via tachykinin NK2 receptors. We have examined the …