The circadian clock is an evolutionarily highly conserved endogenous timing program that
structures physiology and behavior according to the time of day. Disruption of circadian …

The circadian system is responsible for internal functions and regulation of the organism
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …

The concentration of biomolecules in living systems shows numerous systematic and
random variations. Systematic variations can be classified based on the frequency of …

The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and
speaking. Almost all physiological processes display circadian rhythms that are driven by …

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in young people.
Although biologics now enable most children and adolescents with JIA to enjoy clinical …

The old people often suffer from circadian rhythm disturbances, which in turn accelerate
aging. Many aging-related degenerative diseases such as Alzheimer's disease, Parkinson's …

Circadian rhythm perturbations can impact the evolution of different conditions, including
autoimmune diseases. This narrative review summarizes the current understanding of …

The circadian rhythm is a self-sustaining 24 h cycle that regulates physiological processes
within the body, including cycles of alertness and sleepiness. Cells have their own intrinsic …

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease affecting young
people. It has a profound impact on their physical, mental and social lives, leading to long …

Shift work is associated with systemic chronic inflammation, impaired host and tumor
defense and dysregulated immune responses to harmless antigens such as allergens or …