Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

The global agenda for malaria eradication would benefit from development of a highly
efficacious vaccine that protects against disease and interrupts transmission of Plasmodium …

Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …

Plasmodium vivax causes over 100 million clinical infections each year. Primarily because
of the lack of a suitable culture system, our understanding of the biology of this parasite lags …

Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading
to identifiable signatures of balancing selection. To comprehensively survey for genes under …

Plasmodium falciparum causes the most severe form of malaria in humans and invades
erythrocytes using multiple ligand-receptor interactions. Two important protein families …

Antibodies that inhibit Plasmodium falciparum invasion of erythrocytes are believed to be an
important component of immunity against malaria. During blood-stage infection, P …

The process of erythrocyte invasion by merozoites of Plasmodium falciparum involves
multiple steps, including the formation of a moving junction between parasite and host cell …

Malaria parasites are obligate intracellular parasites whose invasive stages select and
invade the unique host cell in which they can develop with exquisite specificity and efficacy …

Seventeen million people die of transmittable diseases and 2/3 of the world's population
suffer them annually. Malaria, tuberculosis, AIDS, hepatitis, and reemerging and new …