Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

Electrophilic compounds originating from nature or chemical synthesis have profound effects
on immune cells. These compounds are thought to act by cysteine modification to alter the …

Chemoresistance is a central cause for the tumor management failure. Cancer cells disrupt
the redox homeostasis through reactive oxygen species (ROS) regulatory mechanisms …

Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid
peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight …

Acute kidney injury (AKI) is a worldwide problem, and there is no effective drug to eliminate
AKI. The death of renal cells is an important pathological basis of intrinsic AKI. At present …

There are large between‐and within‐country variations in COVID‐19 death rates. Some very
low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a …

Simple Summary Inflammation is like the proverbial double-edged sword. Controlled short-
term inflammation could be a protective response while uncontrolled inflammation sustains …

Covering: up to 2020 The transcription factor NRF2 is one of the body's major defense
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …

Sepsis is recognized as a life-threatening multi-organ dysfunction resulting from a
dysregulated host response to infection. Although the incidence and mortality of sepsis …