Boman HG (Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm,
Sweden). Antibacterial peptides: basic facts and emerging concepts (Review). J Intern Med …

Cytotoxic T lymphocytes (CTLs) provide potent defences against virus infection and
intracellular pathogens. However, CTLs have a dark side—their lytic machinery can be …

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
adverse drug reactions characterized by massive epidermal necrosis, in which the specific …

Virtually all of the measurable cell-mediated cytotoxicity delivered by cytotoxic T
lymphocytes and natural killer cells comes from either the granule exocytosis pathway or the …

Natural killer (NK) cells are innate effector lymphocytes necessary for defence against
stressed, microbe-infected, or malignant cells. NK cells kill target cells by either of two major …

Amyloid protein is well known to induce neuronal cell death, whereas only little is known
about its effect on astrocytes. We found that amyloid peptides activated caspase 3 and …

Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

Granule exocytosis is the main pathway for the immune elimination of virus-infected cells
and tumour cells by cytotoxic T lymphocytes and natural killer cells. After target-cell …

Natural killer (NK) cells are major contributors to immunosurveillance and control of tumor
development by inducing apoptosis of malignant cells. Among the main mechanisms …

Extracellular vesicles (EVs) deliver bioactive macromolecules (ie proteins, lipids and nucleic
acids) for intercellular communication in multicellular organisms. EVs are secreted by all cell …