Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
Metabolic phenotype of bladder cancer
F Massari, C Ciccarese, M Santoni, R Iacovelli… - Cancer treatment …, 2016 - Elsevier
Metabolism of bladder cancer represents a key issue for cancer research. Several metabolic
altered pathways are involved in bladder tumorigenesis, representing therefore interesting …
altered pathways are involved in bladder tumorigenesis, representing therefore interesting …
Comprehensive metabolomics expands precision medicine for triple-negative breast cancer
Y Xiao, D Ma, YS Yang, F Yang, JH Ding, Y Gong… - Cell research, 2022 - nature.com
Metabolic reprogramming is a hallmark of cancer. However, systematic characterizations of
metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the …
metabolites in triple-negative breast cancer (TNBC) are still lacking. Our study profiled the …
[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
Metabolomic approaches for detection and identification of biomarkers and altered pathways in bladder cancer
NA di Meo, D Loizzo, SD Pandolfo, R Autorino… - International Journal of …, 2022 - mdpi.com
Metabolomic analysis has proven to be a useful tool in biomarker discovery and the
molecular classification of cancers. In order to find new biomarkers, and to better understand …
molecular classification of cancers. In order to find new biomarkers, and to better understand …
Cancer metabolomic markers in urine: evidence, techniques and recommendations
SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …
and monitoring of diseases since ancient times. As we progress through the 21st century …
A landscape of metabolic variation across tumor types
Tumor metabolism is reorganized to support proliferation in the face of growth-related stress.
Unlike the widespread profiling of changes to metabolic enzyme levels in cancer …
Unlike the widespread profiling of changes to metabolic enzyme levels in cancer …
Metabolomics and diabetes: analytical and computational approaches
Diabetes is characterized by altered metabolism of key molecules and regulatory pathways.
The phenotypic expression of diabetes and associated complications encompasses …
The phenotypic expression of diabetes and associated complications encompasses …
Dysregulated gut homeostasis observed prior to the accumulation of the brain amyloid-β in Tg2576 mice
P Honarpisheh, CR Reynolds… - International journal of …, 2020 - mdpi.com
Amyloid plaques in Alzheimer's disease (AD) are associated with inflammation. Recent
studies demonstrated the involvement of the gut in cerebral amyloid-beta (Aβ) pathogenesis; …
studies demonstrated the involvement of the gut in cerebral amyloid-beta (Aβ) pathogenesis; …
[HTML][HTML] Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation
J Sun, S Osenberg, A Irwin, LH Ma, N Lee, Y Xiang… - Cell reports, 2023 - cell.com
Mutations in the MECP2 gene underlie a spectrum of neurodevelopmental disorders, most
commonly Rett syndrome (RTT). We ask whether MECP2 mutations interfere with human …
commonly Rett syndrome (RTT). We ask whether MECP2 mutations interfere with human …