Metastasis is a major cause of death in patients with cancer. The two main routes for cancer
cell dissemination are the blood and lymphatic systems. The underlying mechanism of …

Background Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs)
played important regulatory roles in many cancer types. However, the role of lncRNAs in …

Aims Lymphatic vessel dysfunction is an emerging component of metabolic diseases and
can lead to tissue lipid accumulation, dyslipidaemia, and oedema. While lymph leakage has …

Highlights•Tumours induce growth and remodelling of lymphatics which is linked with
metastasis.•Lymphatic vessels modulate antitumour immunity in tumours and draining lymph …

The lymphatic system is essential for the maintenance of tissue fluid homeostasis,
gastrointestinal lipid absorption, and immune trafficking. Whereas lymphatic regeneration …

Nanovaccines, a new generation of vaccines that use nanoparticles as carriers and/or
adjuvants, have been widely used in the prevention and treatment of various diseases …

Lymph node metastasis is one of the most malignant clinical features in patients with
esophageal squamous cell carcinoma (ESCC). Understanding the mechanism of lymph …

In this paper, a reaction–diffusion within-host HIV model is proposed. It incorporates cell
mobility, spatial heterogeneity and cell-to-cell transmission, which depends on the diffusion …

The lymphatic vasculature has traditionally been thought to play a passive role in the
regulation of immune responses by transporting antigen presenting cells and soluble …

The ever-growing research on lymphatic biology has clearly identified lymphatic vessels as
key players that maintain human health through their functional roles in tissue fluid …