Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

[HTML][HTML] Primary Progressive Multiple Sclerosis—A Key to Understanding and Managing Disease Progression

I Sempik, E Dziadkowiak, H Moreira, A Zimny… - International Journal of …, 2024 - mdpi.com
Primary progressive multiple sclerosis (PPMS), the least frequent type of multiple sclerosis
(MS), is characterized by a specific course and clinical symptoms, and it is associated with a …

Urine-derived stem cells serve as a robust platform for generating native or engineered extracellular vesicles

AT Boysen, B Whitehead, ALS Revenfeld… - Stem Cell Research & …, 2024 - Springer
Background Mesenchymal stromal cell (MSC) therapy holds great potential yet efficacy and
safety concerns with cell therapy persist. The beneficial effects of MSCs are often attributed …

[HTML][HTML] Brain incoming call from glia during neuroinflammation: Roles of extracellular vesicles

F D'Egidio, V Castelli, M d'Angelo, F Ammannito… - Neurobiology of …, 2024 - Elsevier
The functionality of the central nervous system (CNS) relies on the connection, integration,
and the exchange of information among neural cells. The crosstalk among glial cells and …

Ultrastructural Characterization of PBMCs and Extracellular Vesicles in Multiple Sclerosis: A Pilot Study

R De Masi, S Orlando, E Carata… - International Journal of …, 2024 - mdpi.com
Growing evidence identifies extracellular vesicles (EVs) as important cell-to-cell signal
transducers in autoimmune disorders, including multiple sclerosis (MS). If the etiology of MS …

Urine-derived stem cells; A robust platform for generating native or engineered autologous Extracellular Vesicles

AT Boysen, B Whitehead, D Gupta, T Petersen… - 2024 - researchsquare.com
Background Mesenchymal stem cell (MSC) therapy holds great potential as a treatment
form, yet efficacy and safety concerns with cell therapy persist. The beneficial effects of …