A library of six novel bis-Schiff base derivatives (2a-f) were synthesized, characterized
through modern spectroscopic techniques and screened for their α-glucosidase and α …

In this study, novel selective antitumor compounds were synthesized based on their
fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A molecular …

Drug repurposing is an emerging field in drug development that has provided many
successful drugs. In the current study, paracetamol, a known antipyretic and analgesic …

Semi-synthetic modifications of natural products have yielded numerous anti-cancer drugs,
antimicrobials, and corrosion inhibitors. In this study, eugenol, a natural product, was …

Due to chronic inflammation, elevated cyclooxygenase (COX-2) level leads to
tumorigenesis, proliferation, invasion, angiogenesis and metastasis. Therefore, suppression …

Aim: To synthesize new hybrid cinnamic acids (10a, 10b and 11) and ester derivatives (7, 8
and 9) and investigate their anti-breast cancer activities. Materials & methods: Compounds 7 …

This work describes the synthesis of para-substituted thiosemicarbazone derivatives by
refluxing 4-ethoxybenzaldehyde (1) and 4-nitrobenzaldehyde (2) with thiosemicarbazide in …

In the present work seven derivatives (5a-5d and 6a-6c) of 2-mercapto-1, 3, 4-oxadiazole
were synthesized by multistep reactions. After characterization through IR, EI-MS, 1 H-, and …

Abstract Synthesis of 7-acetyl-2-aryl-5-nitrobenzofurans 2a–j involved sequential
Sonogashira cross-coupling of 2-hydroxy-3-iodo-5-nitroacetophenone with terminal …

This research is based on the synthesis, characterization and in vitro α‐glucosidase
inhibitory activity of fourteen amides (2 a–2 n) of flurbiprofen drug. Seven compounds in the …