COVID-19 and respiratory system disorders: current knowledge, future clinical and translational research questions

SB Brosnahan, AH Jonkman, MC Kugler… - … , and vascular biology, 2020 - Am Heart Assoc
The severe acute respiratory syndrome coronavirus-2 emerged as a serious human
pathogen in late 2019, causing the disease coronavirus disease 2019 (COVID-19). The …

Silent hypoxaemia in COVID‐19 patients

TS Simonson, TL Baker, RB Banzett… - The Journal of …, 2021 - Wiley Online Library
The clinical presentation of COVID‐19 due to infection with SARS‐CoV‐2 is highly variable
with the majority of patients having mild symptoms while others develop severe respiratory …

[HTML][HTML] The interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders

J Burtscher, M Niedermeier, K Hüfner… - Neuroscience & …, 2022 - Elsevier
Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations

VS Hernández, MA Zetter, EC Guerra… - Experimental …, 2021 - Elsevier
We examined cell type-specific expression and distribution of rat brain angiotensin-
converting enzyme 2 (ACE2), the receptor for SARS-CoV-2, in the rodent brain. ACE2 is …

Neuromedin B-expressing neurons in the retrotrapezoid nucleus regulate respiratory homeostasis and promote stable breathing in adult mice

GMPR Souza, DS Stornetta, Y Shi, E Lim… - Journal of …, 2023 - Soc Neuroscience
Respiratory chemoreceptor activity encoding arterial Pco2 and Po2 is a critical determinant
of ventilation. Currently, the relative importance of several putative chemoreceptor …

Neuronal networks in hypertension: recent advances

PG Guyenet, RL Stornetta, GMPR Souza… - …, 2020 - Am Heart Assoc
Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

Satellite glial cells and astrocytes, a comparative review

M Hanani, A Verkhratsky - Neurochemical research, 2021 - Springer
Astroglia are neural cells, heterogeneous in form and function, which act as supportive
elements of the central nervous system; astrocytes contribute to all aspects of neural …

Structural basis for pH gating of the two-pore domain K+ channel TASK2

B Li, RA Rietmeijer, SG Brohawn - Nature, 2020 - nature.com
TASK2 (also known as KCNK5) channels generate pH-gated leak-type K+ currents to
control cellular electrical excitability,–. TASK2 is involved in the regulation of breathing by …

[HTML][HTML] Parabrachial tachykinin1-expressing neurons involved in state-dependent breathing control

JW Arthurs, AJ Bowen, RD Palmiter… - Nature …, 2023 - nature.com
Breathing is regulated automatically by neural circuits in the medulla to maintain
homeostasis, but breathing is also modified by behavior and emotion. Mice have rapid …

[HTML][HTML] Breathing control, brain, and bodily self-consciousness: toward immersive digiceuticals to alleviate respiratory suffering

S Betka, D Adler, T Similowski, O Blanke - Biological psychology, 2022 - Elsevier
Breathing is peculiar among autonomic functions through several characteristics. It
generates a very rich afferent traffic from an array of structures belonging to the respiratory …