Polyphenols as antioxidant/pro-oxidant compounds and donors of reducing species: relationship with human antioxidant metabolism

CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Processes, 2023 - mdpi.com
In this review, we have focused mainly on the study of their antioxidant and pro-oxidant
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …

Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects

L Pereira, A Valado - Life, 2023 - mdpi.com
Diabetes poses a significant global health challenge, necessitating innovative therapeutic
strategies. Natural products and their derivatives have emerged as promising candidates for …

Thiazolidine-2, 4-dione derivatives as potential α-glucosidase inhibitors: Synthesis, inhibitory activity, binding interaction and hypoglycemic activity

M Li, J Sun, B Liang, X Min, J Hu, R Wu, X Xu - Bioorganic Chemistry, 2024 - Elsevier
In order to find effective α-glucosidase inhibitors, a series of thiazolidine-2, 4-dione
derivatives (C1∼ 36) were synthesized and evaluated for α-glucosidase inhibitory activity …

Polyphenol Fingerprint, Biological Activities, and In Silico Studies of the Medicinal Plant Cistus parviflorus L. Extract

FAA El-Shibani, GM Sulaiman, AS Abouzied… - ACS …, 2023 - ACS Publications
Cistus parviflorus L.(Cistaceae) is a medicinal plant with several folkloric applications,
including being used for urinary tract infections and as a food additive. In this study, the …

Inhibitory Potential of Different Bilberry (Vaccinium myrtillus L.) Extracts on Human Salivary α-Amylase

D Karcheva-Bahchevanska, M Nikolova, I Iliev - Molecules, 2023 - mdpi.com
Recently, consumer preferences for bilberries have increased markedly. This fact is
probably related to their natural constituents, such as phenolic compounds including …

Ultrasound-Assisted Extraction of Isoquercetin from Ephedra alata (Decne): Optimization Using Response Surface Methodology and In Vitro Bioactivities

E El Maaiden, N Qarah, A Ezzariai, A Mazar, B Nasser… - Antioxidants, 2023 - mdpi.com
Isoquercetin (ISQ) is reported to be a powerful antioxidant with extremely high bioavailability
and structural stability compared to aglycone quercetin. Despite this, it is not well studied …

[HTML][HTML] Structure-function relationships in (poly) phenol-enzyme binding: Direct inhibition of human salivary and pancreatic α-amylases

R Visvanathan, MJ Houghton, E Barber… - Food Research …, 2024 - Elsevier
Abstract (Poly) phenols inhibit α-amylase by directly binding to the enzyme and/or by
forming starch-polyphenol complexes. Conventional methods using starch as the substrate …

Corchorus olitorius extract exhibit anti-hyperglycemic and anti-inflammatory properties in rodent models of obesity and diabetes mellitus

K Mokgalaboni, WN Phoswa - Frontiers in nutrition, 2023 - frontiersin.org
Obesity and type 2 diabetes (T2D) are chronic conditions with detrimental impacts on the
overall health of individuals. Presently, the use of pharmacological agents in obesity and …

The Influence of Ecological Factors on the Phytochemical Characteristics of Pinus cembra L.

NA Coman, M Babotă, I Nădășan, A Nicolescu… - Applied Sciences, 2023 - mdpi.com
Pinus cembra L., also known as Swiss pine, is one of the lesser studied coniferous species,
despite literature pointing out its great potential to be used for medical purposes due to its …

Antiobesity and antidiabetes effects of Cyperus rotundus rhizomes presenting protein tyrosine phosphatase, dipeptidyl peptidase 4, metabolic enzymes, stress oxidant …

FIA Abdella, A Toumi, S Boudriga, TYA Alanazi… - Heliyon, 2024 - cell.com
Diabetes is a significant global health concern that increases the vulnerability to various
chronic illnesses. In view of this issue, the current research aimed to examine the effects of …