Fat body—Multifunctional insect tissue

P Skowronek, Ł Wójcik, A Strachecka - Insects, 2021 - mdpi.com
Simple Summary Efficient and proper functioning of processes within living organisms play
key roles in times of climate change and strong human pressure. In insects, the most …

Regulation of trehalose metabolism in insects: from genes to the metabolite window

MB Tellis, HM Kotkar, RS Joshi - Glycobiology, 2023 - academic.oup.com
Trehalose is a major circulatory sugar in the haemolymph of insects. It provides instant
energy and protection against stress. Trehalose metabolism is associated with insect growth …

Benchmarking AlphaFold2 on peptide structure prediction

EF McDonald, T Jones, L Plate, J Meiler, A Gulsevin - Structure, 2023 - cell.com
Recent advancements in computational tools have allowed protein structure prediction with
high accuracy. Computational prediction methods have been used for modeling many …

Dietary cysteine drives body fat loss via FMRFamide signaling in Drosophila and mouse

T Song, W Qin, Z Lai, H Li, D Li, B Wang, W Deng… - Cell Research, 2023 - nature.com
Obesity imposes a global health threat and calls for safe and effective therapeutic options.
Here, we found that protein-rich diet significantly reduced body fat storage in fruit flies, which …

Fat enough for the winter? Does nutritional status affect diapause?

CA Short, DA Hahn - Journal of Insect Physiology, 2023 - Elsevier
Many insects enter a dormant state termed diapause in anticipation of seasonal inhospitable
conditions. Insects drastically reduce their feeding during diapause. Their reduced nutrient …

The metabolism and role of free fatty acids in key physiological processes in insects of medical, veterinary and forensic importance

A Kaczmarek, M Boguś - PeerJ, 2021 - peerj.com
Insects are the most widespread group of organisms and more than one million species
have been described. These animals have significant ecological functions, for example they …

Endocrine regulation of immunity in insects

C Nunes, É Sucena, T Koyama - The FEBS journal, 2021 - Wiley Online Library
Organisms have constant contact with potentially harmful agents that can compromise their
fitness. However, most of the times these agents fail to cause serious disease by virtue of the …

[HTML][HTML] The insulin receptor: an important target for the development of novel medicines and pesticides

X Zhang, X Zhu, X Bi, J Huang, L Zhou - International journal of molecular …, 2022 - mdpi.com
The insulin receptor (IR) is a transmembrane protein that is activated by ligands in insulin
signaling pathways. The IR has been considered as a novel therapeutic target for clinical …

Examination of the regulation of energy metabolism, antioxidant response, and ammonia detoxification in hard clam, Mercenaria mercenaria, under hypersalinity …

C Zhou, L Xu, H Song, J Feng, Z Hu, MJ Yang, P Shi… - Aquaculture, 2023 - Elsevier
With global warming on the rise, hypersalinity events are occurring with increasing
frequency due to accelerated evaporation rates of seawater. Hypersalinity affects the …

Metabolic response of Mercenaria mercenaria under heat and hypoxia stress by widely targeted metabolomic approach

Z Hu, J Feng, H Song, C Zhou, MJ Yang, P Shi… - Science of The Total …, 2022 - Elsevier
In the context of global climatic changes, marine organisms have been exposed to
environmental stressors including heat and hypoxia. This calls for the design of multi …