MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a
length of about 22 nucleotides, which regulate genes expression, through modulating the …

Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNASeq applications …

Desmosomes play a key role in the regulation of cell adhesion and signaling. Dysregulation
of the desmosome complex is associated with the loss of epithelial cell polarity and …

Background Astrocytes are the most numerous glial cell type with important roles in
maintaining homeostasis and responding to diseases in the brain. Astrocyte function is …

Acute lung injury (ALI) is a life-threatening condition with limited treatment options. The
pathogenesis of ALI involves macrophage-mediated disruption and subsequent repair of the …

Background Chagas disease is considered important and presents intense inflammatory
and fibrotic processes induced by the perpetuation of the parasite in the affected tissues and …

Galectins comprise a family of soluble β-galactoside-binding proteins, which regulate a
variety of key biological processes including cell growth, differentiation, survival, and death …

Atherosclerosis is a chronic inflammatory disease in which aberrant lipid metabolism plays a
key role. MicroRNAs (miRNAs), micro-coordinators of gene expression, have been recently …

Post-transcriptional regulation in multicellular organisms is mediated by microRNAs.
However, the principles that determine if a gene is regulated by miRNAs are poorly …

Simple Summary Breast cancer is the most common cancer in women worldwide. The risk of
developing postmenopausal breast cancer is exacerbated by obesity (BMI> 30 kg/m2), and …