Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the
EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown that …

Stroke is a complex disease caused by combination of multiple risk factors. Recent findings
have suggested that stroke has a significant genetic component. Various types of genetic …

Hypertension is a complex, multifactorial disease; genetic factors represent one third to half
of the inter-individual variability of blood pressure values. Among the causes of secondary …

Methods: The study was conducted in 406 hypertensive cases and 424 healthy controls from
Tamil population. Genotyping was performed by PCR-restriction fragment length …

Resistant hypertension (RH) is the maintenance of elevated blood pressure concurrent with
the use of three different anti-hypertensive drugs, one of which is a diuretic. The Renin …

Background The association between aldosterone synthase (CYP11B2) C-344T gene
polymorphism and ischemic stroke remains controversial and ambiguous. To better explain …

Left ventricular (LV) hypertrophy in subjects with hypertrophic cardiomyopathy (HCM) is
variable, suggesting a role for modifying factors. Here, we determined whether aldosterone …

Skinfold thickness and blood pressure across C-344T polymorp... : Journal of Hypertension
Skinfold thickness and blood pressure across C-344T polymorphism of CYP11B2 gene : Journal …

Aim: the aim of the present study is to evaluate the association between CYP11B2gene and
type 2 diabetic nephropathy patients in Indian population. Result: There was a significant …

Objective: The Aldosterone synthase (CYP11B2) is a key enzyme that plays a role in the
production of aldosterone. The existence of a common polymorphism in the gene of this …