Collagen as a biomaterial for skin and corneal wound healing

R Sklenářová, N Akla, MJ Latorre, J Ulrichová… - Journal of Functional …, 2022 - mdpi.com
The cornea and the skin are two organs that form the outer barrier of the human body. When
either is injured (eg, from surgery, physical trauma, or chemical burns), wound healing is …

Innovations in the treatment of dystrophic epidermolysis bullosa (DEB): current landscape and prospects

PC Hou, N Del Agua, SM Lwin, CK Hsu… - … and Clinical Risk …, 2023 - Taylor & Francis
Dystrophic epidermolysis bullosa (DEB) is one of the major types of EB, a rare hereditary
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …

Extracellular matrix stiffness—The central cue for skin fibrosis

K Wang, D Wen, X Xu, R Zhao, F Jiang… - Frontiers in Molecular …, 2023 - frontiersin.org
Skin fibrosis is a physiopathological process featuring the excessive deposition of
extracellular matrix (ECM), which is the main architecture that provides structural support …

The two sides of chromosomal instability: drivers and brakes in cancer

R Hosea, S Hillary, S Naqvi, S Wu… - Signal Transduction and …, 2024 - nature.com
Chromosomal instability (CIN) is a hallmark of cancer and is associated with tumor cell
malignancy. CIN triggers a chain reaction in cells leading to chromosomal abnormalities …

Skin-Derived ABCB5+ Mesenchymal Stem Cells for High-Medical-Need Inflammatory Diseases: From Discovery to Entering Clinical Routine

E Niebergall-Roth, NY Frank, C Ganss… - International Journal of …, 2022 - mdpi.com
The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident
mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing …

Squamous cell carcinoma in patients with inherited epidermolysis bullosa: Review of current literature

D Bonamonte, A Filoni, A De Marco, L Lospalluti… - Cells, 2022 - mdpi.com
Epidermolysis bullosa (EB) is a group of rare congenital diseases caused by mutations in
structural proteins of the dermal/epidermal junction that are characterized by extreme …

Stairways to advanced therapies for epidermolysis bullosa

L De Rosa, E Enzo, M Palamenghi… - Cold Spring …, 2023 - cshperspectives.cshlp.org
Epidermolysis bullosa (EB) is a devastating genetic skin disease typified by a plethora of
different phenotypes and ranking from severe, early lethal, to mild localized forms. Although …

[HTML][HTML] Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

F Cheng, VC Hansson, G Georgolopoulos, K Mani - Oncotarget, 2023 - ncbi.nlm.nih.gov
Abstract Glypicans (GPC1-6) are associated with tumorigenic processes and their
involvement in neoplastic behavior has been discussed in different cancer types. Here, a …

Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa–Associated Cutaneous Squamous Cell Carcinoma

CAA Lee, S Wu, YT Chow, E Kofman, V Williams… - Journal of Investigative …, 2024 - Elsevier
Recessive dystrophic epidermolysis bullosa (RDEB) is a severely debilitating disorder
caused by pathogenic variants in COL7A1 and is characterized by extreme skin fragility …

Longitudinal study of wound healing status and bacterial colonisation of Staphylococcus aureus and Corynebacterium diphtheriae in epidermolysis bullosa patients

I Fuentes, MJ Yubero, P Morandé… - International Wound …, 2023 - Wiley Online Library
Epidermolysis bullosa (EB) is an inherited disorder characterised by skin fragility and the
appearance of blisters and wounds. Patient wounds are often colonised or infected with …