Oxygen levels in the placental microenvironment throughout gestation are not constant, with
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …

Background. Epidemiological evidence continues to accumulate on the effect of
psychosocial and behavioral factors in relation to cancer risk, progression, and mortality …

Microplastics (MPs) generally refer to the plastic fragments or particles smaller than 5 mm in
diameter, which are closely concerned due to their widespread presence in the …

Ischemia-reperfusion (I/R) injury is a manifestation of tissue or organ damage that is
followed by ischemia and exacerbated by the return of blood flow to a previously damaged …

Melanoma is the most aggressive skin cancer, with a growing number of incidents
worldwide and with no effective cure in a metastatic stage so far. There are several …

Aging biology is intimately associated with dysregulated metabolism, which is one of the
hallmarks of aging. Aging‐related pathways such as mTOR and AMPK, which are major …

Arteriosclerosis causes significant morbidity and mortality worldwide. Central to this process
is the development of subclinical non-atherosclerotic intimal lesions before the appearance …

Oxidative stress results from an imbalance between reactive oxygen species (ROS)
production and antioxidant defense mechanisms. The regulation of stem cell self‐renewal …

Over the last decade, mesenchymal stem cells (MSCs) have been considered a suitable
source for cell-based therapy, especially in regenerative medicine. First, the efficacy and …

Providing a conducive microenvironment is critical to increase survival of transplanted stem
cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac …