The impact of hypoxia in early pregnancy on placental cells
H Zhao, RJ Wong, DK Stevenson - International journal of molecular …, 2021 - mdpi.com
Oxygen levels in the placental microenvironment throughout gestation are not constant, with
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
Psychological stress and cellular aging in cancer: A meta‐analysis
J Kruk, BH Aboul-Enein, J Bernstein… - … medicine and cellular …, 2019 - Wiley Online Library
Background. Epidemiological evidence continues to accumulate on the effect of
psychosocial and behavioral factors in relation to cancer risk, progression, and mortality …
psychosocial and behavioral factors in relation to cancer risk, progression, and mortality …
Polystyrene microplastics induce apoptosis and necroptosis in swine testis cells via ROS/MAPK/HIF1α pathway
X Wang, X Zhang, K Sun, S Wang… - Environmental …, 2022 - Wiley Online Library
Microplastics (MPs) generally refer to the plastic fragments or particles smaller than 5 mm in
diameter, which are closely concerned due to their widespread presence in the …
diameter, which are closely concerned due to their widespread presence in the …
Oxidative stress in intestinal ischemia-reperfusion
G Li, S Wang, Z Fan - Frontiers in Medicine, 2022 - frontiersin.org
Ischemia-reperfusion (I/R) injury is a manifestation of tissue or organ damage that is
followed by ischemia and exacerbated by the return of blood flow to a previously damaged …
followed by ischemia and exacerbated by the return of blood flow to a previously damaged …
Oxidative stress in melanogenesis and melanoma development
K Kamiński, U Kazimierczak, T Kolenda - Contemporary Oncology …, 2022 - termedia.pl
Melanoma is the most aggressive skin cancer, with a growing number of incidents
worldwide and with no effective cure in a metastatic stage so far. There are several …
worldwide and with no effective cure in a metastatic stage so far. There are several …
The aging metabolome—biomarkers to hub metabolites
R Sharma, A Ramanathan - Proteomics, 2020 - Wiley Online Library
Aging biology is intimately associated with dysregulated metabolism, which is one of the
hallmarks of aging. Aging‐related pathways such as mTOR and AMPK, which are major …
hallmarks of aging. Aging‐related pathways such as mTOR and AMPK, which are major …
Reactive oxygen species (ROS), intimal thickening, and subclinical atherosclerotic disease
D Burtenshaw, M Kitching, EM Redmond… - Frontiers in …, 2019 - frontiersin.org
Arteriosclerosis causes significant morbidity and mortality worldwide. Central to this process
is the development of subclinical non-atherosclerotic intimal lesions before the appearance …
is the development of subclinical non-atherosclerotic intimal lesions before the appearance …
Pharmacological regulation of oxidative stress in stem cells
J Lee, YS Cho, H Jung, I Choi - Oxidative Medicine and Cellular …, 2018 - Wiley Online Library
Oxidative stress results from an imbalance between reactive oxygen species (ROS)
production and antioxidant defense mechanisms. The regulation of stem cell self‐renewal …
production and antioxidant defense mechanisms. The regulation of stem cell self‐renewal …
The secretome of mesenchymal stem cells and oxidative stress: challenges and opportunities in cell-free regenerative medicine
Over the last decade, mesenchymal stem cells (MSCs) have been considered a suitable
source for cell-based therapy, especially in regenerative medicine. First, the efficacy and …
source for cell-based therapy, especially in regenerative medicine. First, the efficacy and …
MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro
Providing a conducive microenvironment is critical to increase survival of transplanted stem
cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac …
cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac …