Angiogenesis in adipose tissue and obesity

S Corvera, J Solivan-Rivera, Z Yang Loureiro - Angiogenesis, 2022 - Springer
While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

New insights on the cardiovascular effects of IGF-1

M Macvanin, Z Gluvic, J Radovanovic… - Frontiers in …, 2023 - frontiersin.org
Introduction Cardiovascular (CV) disorders are steadily increasing, making them the world's
most prevalent health issue. New research highlights the importance of insulin-like growth …

Insulin-like growth factor-1 receptor controls the function of CNS-resident macrophages and their contribution to neuroinflammation

DC Ivan, KC Berve, S Walthert, G Monaco… - Acta neuropathologica …, 2023 - Springer
Signaling by insulin-like growth factor-1 (IGF-1) is essential for the development of the
central nervous system (CNS) and regulates neuronal survival and myelination in the adult …

Exploring the therapeutic potential of targeting GH and IGF-1 in the management of obesity: insights from the interplay between these hormones and metabolism

S Al-Samerria, S Radovick - International journal of molecular sciences, 2023 - mdpi.com
Obesity is a growing public health problem worldwide, and GH and IGF-1 have been studied
as potential therapeutic targets for managing this condition. This review article aims to …

Physiological response of endurance exercise as a growth hormone mediator in adolescent women's

Sugiharto, D Merawati, A Pranoto… - Journal of basic and …, 2023 - degruyter.com
Objectives Overweight status decreases the growth hormone (GH) secretion, thus,
increasing the risk factors for medical complications. However, proper exercise is reported to …

Platelet-Rich Plasma Power-Mix Gel (ppm)—An Orthobiologic Optimization Protocol Rich in Growth Factors and Fibrin

JF Lana, J Purita, PA Everts, PAT De Mendonça Neto… - Gels, 2023 - mdpi.com
Platelet-and fibrin-rich orthobiologic products, such as autologous platelet concentrates,
have been extensively studied and appreciated for their beneficial effects on multiple …

Development of dementia in type 2 diabetes patients: mechanisms of insulin resistance and antidiabetic Drug Development

DD Singh, AA Shati, MY Alfaifi, SEI Elbehairi, I Han… - Cells, 2022 - mdpi.com
Dementia is reported to be common in those with type 2 diabetes mellitus. Type 2 diabetes
contributes to common molecular mechanisms and an underlying pathology with dementia …

Cognitive Deficits in Aging Related to Changes in Basal Forebrain Neuronal Activity

I Chaves-Coira, N García-Magro, J Zegarra-Valdivia… - Cells, 2023 - mdpi.com
Aging is a physiological process accompanied by a decline in cognitive performance. The
cholinergic neurons of the basal forebrain provide projections to the cortex that are directly …

Positive effects of dietary Clostridium butyricum supplementation on growth performance, antioxidant capacity, immunity and viability against hypoxic stress in …

P Li, X Chen, D Hou, B Chen, K Peng… - Frontiers in …, 2023 - frontiersin.org
The effects of dietary supplementation of Clostridium butyricum (CB) on growth performance,
serum biochemistry, antioxidant activity, mRNA levels of immune-related genes and …

Increased GH secretion and body growth in mice carrying ablation of IGF-1 receptor in GH-releasing hormone cells

DO Gusmao, ME de Sousa, MR Tavares… - …, 2022 - academic.oup.com
Growth hormone (GH) secretion is controlled by short and long negative feedback loops. In
this regard, both GH (short-loop feedback) and insulin-like growth factor 1 (IGF-1; long-loop …