Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Immunopathology of chronic hepatitis B infection: role of innate and adaptive immune response in disease progression

A Khanam, JV Chua, S Kottilil - International Journal of Molecular …, 2021 - mdpi.com
More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …

Pathogenicity and virulence of Hepatitis B virus

YC Chuang, KN Tsai, JHJ Ou - Virulence, 2022 - Taylor & Francis
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

Identification of anoikis-related subgroups and prognosis model in liver hepatocellular carcinoma

Y Chen, W Huang, J Ouyang, J Wang, Z Xie - International journal of …, 2023 - mdpi.com
Resistance to anoikis is a key characteristic of many cancer cells, promoting cell survival.
However, the mechanism of anoikis in hepatocellular carcinoma (HCC) remains unknown …

[HTML][HTML] The emerging importance role of m6A modification in liver disease

S Wang, S Gao, W Ye, Y Li, J Luan, X Lv - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract N6-methyladenosine (m6A) modification, as one of the most common types of inner
RNA modification in eukaryotes, plays a multifunctional role in normal and abnormal …

[HTML][HTML] An immune subtype-related prognostic signature of hepatocellular carcinoma based on single-cell sequencing analysis

J Xie, L Chen, Q Sun, H Li, W Wei, D Wu, Y Hu… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and is
often associated with a poor prognosis. The main reason for this poor prognosis is that …

HBV induced hepatocellular carcinoma and related potential immunotherapy

L Jia, Y Gao, Y He, JD Hooper, P Yang - Pharmacological Research, 2020 - Elsevier
Chronic infection of Hepatitis B virus (HBV) has long been recognized as a major risk factor
in the initiation and development of hepatocellular carcinoma (HCC), contributing to over …

Innate lymphocytes: pathogenesis and therapeutic targets of liver diseases and cancer

Y Chen, Z Tian - Cellular & molecular immunology, 2021 - nature.com
The liver is a lymphoid organ with unique immunological properties, particularly, its
predominant innate immune system. The balance between immune tolerance and immune …

Relevance of HBx for hepatitis B virus-associated pathogenesis

A Schollmeier, M Glitscher, E Hildt - International Journal of Molecular …, 2023 - mdpi.com
The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …