Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis

C Chen, J Liu, X Lin, A Xiang, Q Ye, J Guo, T Rui… - Cell Death …, 2024 - nature.com
Abstract Cancer-associated fibroblasts (CAFs), the main stromal component of the tumor
microenvironment (TME), play multifaceted roles in cancer progression through paracrine …

Inhibition of PCSK9: a promising enhancer for anti-PD-1/PD-L1 immunotherapy

S Sun, J Ma, T Zuo, J Shi, L Sun, C Meng, W Shu… - Research, 2024 - spj.science.org
Immune checkpoint therapy, such as programmed cell death protein 1/programmed death-
ligand 1 (PD-1/PD-L1) blockade, has achieved remarkable results in treating various tumors …

Unveiling the oncogenic role of CLDN11-secreting fibroblasts in gastric cancer peritoneal metastasis through single-cell sequencing and experimental approaches

K Liu, Y Wang, W Shao, C Tang, S Zhao, J Xu… - International …, 2024 - Elsevier
Background Fibroblasts are necessary to the progression of cancer. However, the role of
fibroblasts in peritoneal metastasis (PM) of gastric cancer (GC) remains elusive. In this study …

Establishment and characterization of a novel multidrug-resistant pancreatic ductal adenocarcinoma cell line, PDAC-X1

C Yu, Y Su, X Miao, C Chai, H Tang, L Li, J Yi, Z Ye… - BMC cancer, 2024 - Springer
Drug resistance remains a significant challenge in the treatment of pancreatic cancer. The
development of drug-resistant cell lines is crucial to understanding the underlying …

A novel multidrug-resistant cell line from a Chinese patient with pancreatic ductal adenocarcinoma

H Tang, X Miao, C Yu, C Chai, Y Su, L Li, J Yi, Z Ye… - Scientific Reports, 2024 - nature.com
Chemotherapy resistance poses clinical challenges in pancreatic cancer treatment.
Developing cell lines resistant to chemotherapy is crucial for investigating drug resistance …

Role of Epiregulin on Lipopolysaccharide-Induced Hepatocarcinogenesis as a Mediator via EGFR Signaling in the Cancer Microenvironment

T Kubo, N Nishimura, K Kaji, F Tomooka… - International Journal of …, 2024 - mdpi.com
Lipopolysaccharides (LPSs) have been reported to be important factors in promoting the
progression of hepatocellular carcinoma (HCC), but the corresponding molecular …

LncRNAPVT1 is Associated with Cancer-Associated Fibroblasts Proliferation Through Regulating TGF-βin Oral Squamous Cell Carcinoma

Z Meng, T Li, J Li, S Ding, Y Liu, G Zhao… - Immunological …, 2024 - Taylor & Francis
Introduction Human oral squamous cell carcinoma (OSCC) is the most common type of oral
cancer and has a poor survival rate. Cell-cell communication between OSCC cells and …

LIN28A/B 在肿瘤发生发展中的作用研究进展

张译文, 黄琴, 吴艳芸, 孙月, 韦永龙 - 遗传, 2024 - chinagene.cn
LIN28A/B 在肿瘤发生发展中的作用研究进展 Page 1 Hereditas (Beijing) www.chinagene.cn 收稿
日期: 2024-03-07; 修回日期: 2024-05-07; 网络发布日期:2024-05-23 基金项目: 云南省肿瘤免疫 …

Role of Epiregulin on Lipopolysaccharide-Induced Hepatocarcinogenesis as a Mediator in the Cancer Microenvironment

T Kubo, N Nishimura, K Kaji, F Tomooka, A Shibamoto… - 2024 - preprints.org
Lipopolysaccharides (LPS) have been reported to be important factors in promoting the
progression of hepatocellular carcinoma (HCC), but the corresponding molecular …