Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon,
inevitable in kidney transplantation and one of the most important mechanisms for non-or …

Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

The pathologic paradigm for renal progression is advancing tubulointerstitial fibrosis.
Whereas mechanisms underlying fibrogenesis have grown in scope and understanding in …

Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …

Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving
systemic organs and apparatus, associated with elevated cardiovascular morbidity and …

Mechanisms of progression of chronic kidney disease (CKD), a major health care burden,
are poorly understood. EGFR stimulates CKD progression, but the molecular networks that …

Dapagliflozin, a new type of drug used to treat diabetes mellitus (DM), is a sodium/glucose
cotransporter 2 (SGLT2) inhibitor. Although some studies showed that SGLT2 inhibition …

Chronic kidney disease (CKD) is characterized by irreversible pathological processes that
result in the development of end-stage renal disease (ESRD). Accumulating evidence has …

Acute kidney injury and maladaptive tubular repair leading t... : Current Opinion in Nephrology
and Hypertension Acute kidney injury and maladaptive tubular repair leading to renal fibrosis …

We conducted a two-stage genome-wide association study of renal cell carcinoma (RCC) in
3,772 affected individuals (cases) and 8,505 controls of European background from 11 …