The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory
nerve terminals, and by suppressing neurotransmitter release, its activation modulates …

Previous studies have shown that ovarian estrogens are involved in the occurrence and
pathology of Alzheimer's disease (AD) through regulation on hippocampal synaptic plasticity …

The serum and glucocorticoid-regulated kinase 1 (SGK1) is a widely expressed protein in
the Central Nervous System (CNS), involved in regulating the activity of a wide variety of ion …

The expression of genes altered in epilepsy remains incomplete, particularly in the
hippocampus, which exhibits exquisite vulnerability to epilepsy. Q808 is an innovation …

Mutations within the Kv7. 2 and Kv7. 3 genes are well described causes for genetic
childhood epilepsies. Knowledge on these channels in acquired focal epilepsy, especially in …

Epilepsy is a neurological condition associated to significant brain damage produced by
status epilepticus (SE) including neurodegeneration, gliosis and ectopic neurogenesis …

In the central nervous system, the M-current plays a critical role in regulating subthreshold
electrical excitability of neurons, determining their firing properties and responsiveness to …

Mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) are two nuclear receptors
that regulate transcription when they bind to their preferred corticosteroid hormone. The …

La epilepsia es un trastorno neurológico caracterizado por convulsiones o crisis recurrentes
no provocadas, desencadenadas por una descarga paroxística anormal y síncrona de una …

Actualmente, el dolor crónico es uno de los motivos de mayor incidencia de consulta
médica. Una quinta parte de los pacientes que refieren dolor crónico es de tipo neuropático …