Objectives: This study evaluated the physiologic characteristics of discordant lesions
between instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) and the …

Although clinical outcomes after percutaneous coronary intervention (PCI) are improving,
the long-term risk for target vessel failure remains concerning. Although the application of …

Around 40% of all patients undergoing angiography are found to have normal coronary
arteries or non-obstructive coronary artery disease (NOCAD). Despite the high prevalence …

High-risk coronary plaque refers to a distinct set of plaque characteristics prone to future
coronary events. Coronary physiology represents a group of indexes reflective of the local …

Stable coronary artery disease (CAD) has recently been replaced by a new entity described
as chronic coronary syndrome (CCS). This new entity has been developed based on a …

Fractional flow reserve is the current invasive gold standard for assessing the ischemic
potential of an angiographically intermediate coronary stenosis. Procedural cost and time …

Background Management of coronary artery disease in patients undergoing transcatheter
aortic valve implantation is uncertain. Fractional flow reserve (FFR) has never been clinically …

Objectives The aims of the present study were to investigate the applicability of quantitative
flow ratio (QFR) in patients with 3-vessel disease and to demonstrate the impact of functional …

Background Although physiology‐based assessment of coronary artery stenosis using
instantaneous wave‐free ratio (iFR) and fractional flow reserve (FFR) are established …

Background: Intraseptal anomalous aortic origin of a coronary artery is considered a benign
condition. However, there have been case reports of patients with myocardial ischemia …