Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …

The use of high-risk renal grafts for transplantation requires optimization of pretransplant
preservation and assessment strategies to improve clinical outcomes as well as to decrease …

Great efforts have been made toward addressing the demand for donor kidneys. One of the
most promising approaches is to use kidneys from donation after circulatory death donors …

Normothermic machine perfusion (NMP) has emerged as a promising tool for the
preservation, viability assessment, and repair of deceased-donor kidneys prior to …

Organ transplantation remains the treatment of last resort in case of failure of a vital organ
(lung, liver, heart, intestine) or non-vital organ (essentially the kidney and pancreas) for …

Background. Normothermic machine perfusion (NMP) is a promising modality for marginal
donor kidneys. However, little is known about the effects of NMP on causing endothelial …

Background. Normothermic machine perfusion (NMP) is typically performed after a period of
hypothermic preservation, which exposes the kidney to an abrupt increase in temperature …

Establishing an objective quality assessment of an organ prior to transplantation can help
prevent unnecessary discard of the organ and reduce the probability of functional failure. In …

Marginal donor kidneys are more likely to develop ischemia-reperfusion injury (IRI),
resulting in inferior long-term outcomes. Perfusion techniques are used to attenuate IRI and …

Background: Normothermic machine perfusion (NMP) has reshaped organ preservation in
recent years. In this preclinical study, prolonged normothermic perfusions of discarded …