Antioxidant Metabolism Pathways in Vitamins, Polyphenols, and Selenium: Parallels and Divergences

CMC Andrés, JM Pérez de la Lastra, CA Juan… - International Journal of …, 2024 - mdpi.com
Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance
between reactive oxygen and nitrogen species in the body and its ability to neutralize them …

Therapeutic effect of trace elements on multiple myeloma and mechanisms of cancer process

K Jahankhani, N Taghipour, MM Rafiee… - Food and Chemical …, 2023 - Elsevier
In the human body, trace elements and other micronutrients play a vital role in growth, health
and immune system function. The trace elements are Iron, Manganese, Copper, Iodine, Zinc …

First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease

P Pyka, W Haberek, M Więcek… - Journal of Medicinal …, 2024 - ACS Publications
Alzheimer's disease (AD) has a complex and not-fully-understood etiology. Recently, the
serotonin receptor 5-HT6 emerged as a promising target for AD treatment; thus, here a new …

Plant-derived selenium nanoparticles: investigating unique morphologies, enhancing therapeutic uses, and leading the way in tailored medical treatments

A Puri, P Mohite, Y Ansari, N Mukerjee… - Materials …, 2024 - pubs.rsc.org
Selenium (Se) stands as a paramount micronutrient, indispensable for the holistic health of
humans, animals, and microorganisms. At its core, Se is instrumental for the genesis of …

[HTML][HTML] Selenium-containing compounds: a new hope for innovative treatments in Alzheimer's disease and Parkinson's disease

P Pyka, S Garbo, R Fioravanti, C Jacob, M Hittinger… - Drug Discovery …, 2024 - Elsevier
Neurodegenerative diseases are challenging to cure. To date, no cure has been found for
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …

Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines

NS da Costa, LS Lima, FAM Oliveira, MEA Galiciolli… - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive, fast-growing tumor that is more likely
to spread to distant organs. Among women diagnosed with breast cancer, the prevalence of …

Photocatalytic Thio/Selenosulfonylation–Bicyclization of Indole-Tethered 1,6-Enynes Leading to Substituted Benzo[c]pyrrolo[1,2,3-lm]carbazoles

HD Zuo, X Chen, Y Zhang, JW Liu, SH Yan, G Li… - Organic …, 2024 - ACS Publications
The photocatalyzed radical-triggered thio/selenosulfonylation–bicyclization of indole-
tethered 1, 6-enynes has been established for the first time, enabling the synthesis of …

Light-assisted Green and Efficient Construction of Thiadiazole/Selenadiazole Derivatives

C Wen, G Sun, L Liu, J Zhang, M She, Z Yang, P Liu… - Green …, 2024 - pubs.rsc.org
Thiadiazole and selenadiazole derivatives are significant organic backbones widely utilized
in drugs, bioactive molecules, and functional materials. A green and efficient one-pot …

Selenium Nanoparticles Show Anticancer Activity Through Regulation of HIF-1α and HIF-2α Under Hypoxic Condition in Liver Cancer Cells

S Acharya, S Nithyananthan… - DNA and Cell …, 2023 - liebertpub.com
Tumor microenvironment has significant influence in therapeutic response and clinical
outcome. Combination therapy is more effective in cancer treatment compared with …

PLGA and PDMS-based in situ forming implants loaded with rosuvastatin and copper-selenium nanoparticles: a promising dual-effect formulation with augmented …

A Maged, M Mabrouk, HT Nour El-Din… - Frontiers in …, 2024 - frontiersin.org
Breast cancer is among the most prevalent tumors worldwide. In this study, in-situ forming
implants (ISFIs) containing rosuvastatin calcium were prepared using three types of poly (D …