Towards artificial intelligence to multi-omics characterization of tumor heterogeneity in esophageal cancer

J Li, L Li, P You, Y Wei, B Xu - Seminars in Cancer Biology, 2023 - Elsevier
Esophageal cancer is a unique and complex heterogeneous malignancy, with substantial
tumor heterogeneity: at the cellular levels, tumors are composed of tumor and stromal …

[HTML][HTML] Multiparametric detection and outcome prediction of pancreatic cancer involving dual-energy CT, diffusion-weighted MRI, and radiomics

V Koch, N Weitzer, DP Dos Santos, LD Gruenewald… - Cancer Imaging, 2023 - Springer
Background The advent of next-generation computed tomography (CT)-and magnetic
resonance imaging (MRI) opened many new perspectives in the evaluation of tumor …

[HTML][HTML] Orlistat induces ferroptosis in pancreatic neuroendocrine tumors by inactivating the MAPK pathway

M Ye, F Lu, J Chen, P Yu, Y Xu, N He, C Hu… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Orlistat is an antiobesity drug approved by the US Food and Drug
Administration (FDA) with potential antitumor activity against a few malignant tumors …

[HTML][HTML] Recent research hotspots in sequencing and the pancreatic neuroendocrine tumor microenvironment

J Xu, W Zhang, X Lou, Z Ye, Y Qin, J Chen… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Multiple endocrine neoplasia 1 (MEN1) syndrome, a disease arising from a genetic
predisposition to tumor development caused by MEN1 loss-of-function mutations, is …

Models using comprehensive, lesion-level, longitudinal [68Ga] Ga-DOTA-TATE PET-derived features lead to superior outcome prediction in neuroendocrine tumor …

V Santoro-Fernandes, B Schott, A Deatsch… - European Journal of …, 2024 - Springer
Purpose Somatostatin receptor (SSTR) imaging features are predictive of treatment outcome
for neuroendocrine tumor (NET) patients receiving peptide receptor radionuclide therapy …

Unmasking pancreatic cancer: Advanced biomedical imaging for its detection in native versus arterial dual‐energy computed tomography (DECT) scans

J Gotta, LD Gruenewald, SS Martin… - … Journal of Imaging …, 2024 - Wiley Online Library
This study investigates the potential of a machine learning classifier using dual‐energy
computed tomography (DECT) radiomics to differentiate between malignant pancreatic …

Molecular Eye: A System for Precise Diagnosis and Treatment of Major Clinical Diseases Based on Molecular Probe Technology

X Ji, X Chen, K Li, Z Zhang, L Tang, T Li… - … & Biomedical Imaging, 2023 - ACS Publications
With the flourishing development of precision medicine, theranostics, generally recognized
as the integration of diagnosis and treatment, has emerged as a prominent trend in clinical …

[图书][B] Comprehensive, Lesion-Level, Longitudinal Assessment of Metastatic Cancer, and its Clinical Implications

VS Fernandes - 2023 - search.proquest.com
Cancer treatment response assessment is particularly challenging in the setting of
metastatic cancer in part because patients can present with hundreds of metastatic lesions …

PIN1 As A Marker of Metastasis and Survival in Pancreatic Neuroendocrine Tumor Identified by Single-cell Sequencing and Proteomic Profiling

M Wang, T Yin, P Huang, T Qin, D Chen, S Xu, J Gong… - 2022 - researchsquare.com
Background This study aimed to identify new protein markers that can evaluate the
metastatic ability of Pancreatic neuroendocrine tumors (PanNETs) and predict prognosis …