Cancer immunotherapy has fundamentally altered cancer treatment; however, its efficacy is
limited to a subset of patients in most clinical settings. The immune system plays a key role …

Simple Summary Cancer treatments have made remarkable advances with the introduction
of immunotherapy, which recruits the body's immune system to fight cancer. Despite these …

Triple-negative breast cancer (TNBC) presents considerable obstacles because of its highly
aggressive characteristics and limited availability of specific therapeutic interventions. The …

Poor intratumoral infiltration is the major challenge for chimeric antigen receptor (CAR)-T
cell therapy in solid tumors. Hypofractionated radiotherapy (HFRT) has been reported to …

Myeloid-derived suppressor cells (MDSCs) are a group of bone marrow derived
heterogeneous cells, which is known for their immunosuppressive functions especially in …

Chronic inflammation plays a pivotal role in cancer development. Cancer cells interact with
adjacent cellular components (pro-inflammatory cells, intrinsic immune cells, stromal cells …

Lung neuroendocrine neoplasms (NENs) encompass a spectrum of neoplasms that are
subdivided into the well-differentiated neuroendocrine tumors comprising the low-and …

Advances in understanding the genetic basis of cancer have driven alternative treatment
approaches. Recent findings have demonstrated the potential of bacteria and it's …

Ovarian cancer (OC) is highly lethal due to late detection and frequent recurrence. Initial
treatments, comprising surgery and chemotherapy, lead to disease remission but are …

Tumor hypoxia impairs the generation of reactive oxygen species and the induction of
immunogenic cell death (ICD) for photodynamic therapy (PDT), thus impeding its efficacy …