The age-dependent relation of blood pressure to cognitive function and dementia

C Qiu, B Winblad, L Fratiglioni - The Lancet Neurology, 2005 - thelancet.com
The relation of blood pressure with cognitive function and dementia has, in recent years,
received much attention from epidemiological research. Some cross-sectional studies have …

Essential hypertension

FH Messerli, B Williams, E Ritz - The Lancet, 2007 - thelancet.com
Essential hypertension can be defined as a rise in blood pressure of unknown cause that
increases risk for cerebral, cardiac, and renal events. In industrialised countries, the risk of …

2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension …

G Mancia, G De Backer, A Dominiczak… - European heart …, 2007 - academic.oup.com
Recommendations about therapy for hypertension are here preceded by some
considerations on the strength of available evidence on the benefits associated with …

Antihypertensive classes, cognitive decline and incidence of dementia: a network meta-analysis

NL Marpillat, I Macquin-Mavier, AI Tropeano… - Journal of …, 2013 - journals.lww.com
Objectives: Prevention of cognitive decline and dementia with blood pressure lowering
treatments has shown inconsistent results. We compared the effects of different classes of …

The relationship between blood pressure and cognitive function

V Novak, I Hajjar - Nature Reviews Cardiology, 2010 - nature.com
The relationship between blood pressure (BP) and cognitive outcomes in elderly adults has
implications for global health care. Both hypertension and hypotension affect brain perfusion …

Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension

DB Matchar, DC McCrory, LA Orlando… - Annals of internal …, 2008 - acpjournals.org
Background: The relative effectiveness of angiotensin-converting enzyme (ACE) inhibitors
and angiotensin II receptor blockers (ARBs) for lowering blood pressure is unknown …

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

B McGuinness, S Todd, P Passmore… - Cochrane Database of …, 2009 - cochranelibrary.com
Blood pressure lowering in patients without prior cerebrovascular disease for prevention of
cognitive impairment and dementia - McGuinness, B - 2009 | Cochrane Library Skip to Content …

Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders

JM Saavedra - Clinical science, 2012 - portlandpress.com
The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …

Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer's disease: Past, present and future

F Gouveia, A Camins, M Ettcheto, J Bicker… - Ageing Research …, 2022 - Elsevier
Alzheimer's disease (AD) is a well-known neurodegenerative disease characterized by the
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …

The coming of age of the angiotensin hypothesis in Alzheimer's disease: progress toward disease prevention and treatment?

PG Kehoe - Journal of Alzheimer's Disease, 2018 - content.iospress.com
There is wide recognition of a complex association between midlife hypertension and
cardiovascular disease and later development of Alzheimer's disease (AD) and cognitive …