DNA vaccines: an historical perspective and view to the future

MA Liu - Immunological reviews, 2011 - Wiley Online Library
This review provides a detailed look at the attributes and immunologic mechanisms of
plasmid DNA vaccines and their utility as laboratory tools as well as potential human …

[HTML][HTML] Immunologic basis of vaccine vectors

MA Liu - Immunity, 2010 - cell.com
Efforts to make vaccines against infectious diseases as well as immunotherapies for cancer,
autoimmune diseases and allergy have utilized a variety of heterologous expression …

Antigen‐specific immunotherapy of cervical and ovarian cancer

CF Hung, TC Wu, A Monie, R Roden - Immunological reviews, 2008 - Wiley Online Library
We contrast the efforts to treat ovarian cancer and cervical cancer through vaccination
because of their different pathobiology. A plethora of approaches have been developed for …

Current state in the development of candidate therapeutic HPV vaccines

A Yang, J Jeang, K Cheng, T Cheng… - Expert review of …, 2016 - Taylor & Francis
The identification of human papillomavirus (HPV) as an etiological factor for HPV-associated
malignancies creates the opportunity to control these cancers through vaccination …

Therapeutic human papillomavirus vaccines: current clinical trials and future directions

CF Hung, B Ma, A Monie, SW Tsen… - Expert opinion on …, 2008 - Taylor & Francis
Background: Cervical cancer is the second largest cause of cancer deaths in women
worldwide. It is now evident that persistent infection with high-risk human papillomavirus …

Gene-based vaccines: recent technical and clinical advances

JB Ulmer, B Wahren, MA Liu - Trends in molecular medicine, 2006 - cell.com
DNA vaccines have been widely used in efforts to develop vaccines against various
pathogens as well as for cancer, autoimmune diseases and allergy. DNA vaccines offer …

[HTML][HTML] Immunotherapy for cervical cancer: Research status and clinical potential

JH Su, A Wu, E Scotney, B Ma, A Monie, CF Hung… - BioDrugs, 2010 - Springer
The high-risk types of human papillomavirus (HPV) have been found to be associated with
most cervical cancers and play an essential role in the pathogenesis of the disease. Despite …

DNA vaccination against tumors

GJ Prud'homme - The Journal of Gene Medicine: A cross …, 2005 - Wiley Online Library
DNA vaccines have been used to generate protective immunity against tumors in a variety of
experimental models. The favorite target antigens have been those that are frequently …

DNA vaccines against tuberculosis

N Bruffaerts, K Huygen, M Romano - Expert opinion on biological …, 2014 - Taylor & Francis
Introduction: Tuberculosis (TB) remains a major health problem and novel vaccination
regimens are urgently needed. Areas covered: DNA vaccines against TB have been tested …

Genetic approaches for the induction of a CD4+ T cell response in cancer immunotherapy

A Bonehill, C Heirman… - The Journal of Gene …, 2005 - Wiley Online Library
Recently, it has become more and more obvious that not only CD8+ cytotoxic T lymphocytes,
but also CD4+ T helper cells are required for the induction of an optimal, long‐lasting anti …