Objective The aim of this study was to identify the role of Piezo1-mediated
mechanotransduction in entheseal pathological new bone formation and to explore the …

Although studies have identified the presence of gut-associated cells in the enthesis of joints
affected by spondylarthritis (SpA), a direct link through cellular transit between the gut and …

Disclosures: G. Kollias reported personal fees from Biomedcode Hellas SA outside the
submitted work. DLP Baeten reported other from UCB outside the submitted work; and has …

Juvenile idiopathic arthritis (JIA) is a term that collectively refers to a group of chronic
childhood arthritides, which together constitute the most common rheumatic condition in …

Psoriatic arthritis is a chronic inflammatory joint disease occurring in a subgroup of patients
suffering from psoriasis. This article gives an overview of the complexity of psoriatic arthritis …

Objective Adiposity is prevalent among patients with psoriatic arthritis (PsA). However, the
temporal relation is unclear. The present study was undertaken to investigate whether …

The last decade has witnessed an explosion of studies evaluating the impact of the human
microbiota on a variety of disease states. The microbiota can impact diseases in multiple …

Axial SpA (axSpA) is a common rheumatic disease characterized by inflammation leading to
bone formation and functional impairment. TNF-α and IL-17 represent established targets in …

Arthritis is the most common extra‐intestinal complication in inflammatory bowel disease
(IBD). Conversely, arthritis patients are at risk for developing IBD and often display …

Dickkopf-1 (Dkk-1) is a key regulator of bone remodeling in spondyloarthropathies.
Nevertheless, data regarding its expression in cells of pathophysiologic relevance, such as …