The Sertoli cell: one hundred fifty years of beauty and plasticity

LR França, RA Hess, JM Dufour, MC Hofmann… - …, 2016 - Wiley Online Library
It has been one and a half centuries since Enrico Sertoli published the seminal discovery of
the testicular 'nurse cell', not only a key cell in the testis, but indeed one of the most amazing …

Sertoli cells–immunological sentinels of spermatogenesis

G Kaur, LA Thompson, JM Dufour - Seminars in cell & developmental …, 2014 - Elsevier
Testicular germ cells, which appear after the establishment of central tolerance, express
novel cell surface and intracellular proteins that can be recognized as 'foreign antigens' by …

[PDF][PDF] The epididymis

B Robaire - Knobil and Neill's Physiology of Reproduction …, 2006 - reproducao.ufc.br
Throughout embryonic and early postnatal development, the mammalian epididymis
changes from a straight tube to a highly coiled, complex duct that links the efferent ducts to …

Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges

A Komin, LM Russell, KA Hristova… - Advanced drug delivery …, 2017 - Elsevier
Peptides are emerging as a new tool in drug and gene delivery. Peptide-drug conjugates
and peptide-modified drug delivery systems provide new opportunities to avoid macrophage …

Morin ameliorates the testicular apoptosis, oxidative stress, and impact on blood–testis barrier induced by photo-extracellularly synthesized silver nanoparticles

AH Arisha, MM Ahmed, MA Kamel, YA Attia… - … Science and Pollution …, 2019 - Springer
Silver nanoparticles (AgNPs) have been widely produced for different industrial purposes.
Recently, biogenic synthesis of AgNPs has emerged although the extent of effects from …

Germ cell transport across the seminiferous epithelium during spermatogenesis

X Xiao, DD Mruk, CKC Wong, C Yan Cheng - Physiology, 2014 - journals.physiology.org
Transport of germ cells across the seminiferous epithelium is crucial to spermatogenesis. Its
disruption causes infertility. Signaling molecules, such as focal adhesion kinase, c-Yes, c …

RANKL regulates male reproductive function

M Blomberg Jensen, CH Andreassen… - Nature …, 2021 - nature.com
Infertile men have few treatment options. Here, we demonstrate that the transmembrane
receptor activator of NF-kB ligand (RANKL) signaling system is active in mouse and human …

Regulation of epithelial function, differentiation, and remodeling in the epididymis

S Breton, YC Ruan, YJ Park, B Kim - Asian journal of andrology, 2016 - journals.lww.com
The epididymis is a single convoluted tubule lined by a pseudostratified epithelium.
Specialized epididymal epithelial cells, the so-called principal, basal, narrow, and clear …

rpS6 regulates blood-testis barrier dynamics through Arp3-mediated actin microfilament organization in rat Sertoli cells. An in vitro study

KW Mok, H Chen, WM Lee, CY Cheng - Endocrinology, 2015 - academic.oup.com
In the seminiferous epithelium of rat testes, preleptotene spermatocytes residing in the basal
compartment are transported across the blood-testis barrier (BTB) to enter the adluminal …

Oxidative stress, spermatozoa and leukocytic infiltration: relationships forged by the opposing forces of microbial invasion and the search for perfection

RJ Aitken, MA Baker - Journal of reproductive immunology, 2013 - Elsevier
This review addresses the complex relationships that exist between spermatozoa and the
immune system and highlights the role of oxidative stress in regulating the direction and …