Identification of the key roles of protein kinases in cancer has led to extensive efforts to
develop kinase inhibitors for the treatment of a wide range of cancers, and more than 30 …

Inhibitors of eukaryotic protein kinases and phosphatases are a chemically diverse array of
natural and synthetic compounds, including medicines, potions and poisons. These …

Exposure of mammalian cells to DNA-damaging agents induces the ultraviolet (UV)
response, involving transcription factor AP-1, composed of Jun and Fos proteins. We …

Exposure of mammalian cells to radiation triggers the ultraviolet (UV) response, which
includes activation of activator protein-1 (AP-1) and nuclear factor kappa B (NF-κB). This …

The precise role of src‐type kinases as signal transducers has been under intensive
investigation but only in a few instances has their role been revealed in any detail. Thus, src …

Abstract Interleukin-6 (IL-6), leukemia inhibitory factor, oncostatin Μ, IL-11, and ciliary
neurotropic factor are a family of cytokines and neuronal differentiation factors which bind to …

Propolis, a honey bee hive product, is thought to exhibit a broad spectrum of activities
including antibiotic, antiviral, anti-inflammatory and tumor growth inhibition; some of the …

To study the signal transduction mechanisms by which ultraviolet B (UVB) leads to
increased prostaglandin E2 (PGE2) synthesis, human epidermal cultures were irradiated …

Ionizing radiation induces in autocrine growth-regulated carcinoma and malignant glioma
cells powerful cytoprotective responses that confer relative resistance to consecutive …

Adeno-associated virus type 2 (AAV), a single-stranded, DNA-containing, nonpathogenic
human parvovirus, has gained attention as a potentially useful vector for human gene …