The role of immune regulatory molecules in rheumatoid arthritis: Implication for etiopathogenesis and prospective for treatment
M Hemmatzadeh, E Ahangar Parvin… - Journal of Cellular …, 2022 - Wiley Online Library
Rheumatoid arthritis (RA) is considered an autoimmune chronic disorder and the most
common inflammatory arthropathy. Disease progression in RA begins with asymptomatic …
common inflammatory arthropathy. Disease progression in RA begins with asymptomatic …
Abnormal membrane-bound and soluble programmed death ligand 2 (PD-L2) expression in systemic lupus erythematosus is associated with disease activity
M Tong, X Fang, J Yang, P Wu, Y Guo, J Sun - Immunology Letters, 2020 - Elsevier
Programmed death ligand (PD-L) 2 and PD-L1 are the second and first ligands, respectively,
for programmed cell death-1 protein (PD-1), which is one of the key factors responsible for …
for programmed cell death-1 protein (PD-1), which is one of the key factors responsible for …
Diminished PD-L1 regulation along with dysregulated T lymphocyte subsets and chemokine in ANCA-associated vasculitis
ANCA-associated vasculitis (AAV) is a life-threatening disease characterized by small
vessel inflammation and pathogenic self-directed antibodies. Programmed death-ligand 1 …
vessel inflammation and pathogenic self-directed antibodies. Programmed death-ligand 1 …
PD‐1: A critical player and target for immune normalization
X Liu, A Zhao, S Xiao, H Li, M Li, W Guo, Q Han - Immunology, 2024 - Wiley Online Library
Immune system imbalances contribute to the pathogenesis of several different diseases, and
immunotherapy shows great therapeutic efficacy against tumours and infectious diseases …
immunotherapy shows great therapeutic efficacy against tumours and infectious diseases …
Expression of IDO1 and PD-L2 in patients with benign lymphadenopathies and association with autoimmune diseases
M Abdulla, C Sundström, C Lindskog, P Hollander - Biomolecules, 2023 - mdpi.com
The expression patterns of IDO1 and PD-L2 have not been thoroughly investigated in
benign lymphadenopathies. The aim with this study was to elucidate how IDO1 and PD-L2 …
benign lymphadenopathies. The aim with this study was to elucidate how IDO1 and PD-L2 …
A model-based clustering via mixture of hierarchical models with covariate adjustment for detecting differentially expressed genes from paired design
Y Zhang, W Liu, W Qiu - BMC bioinformatics, 2023 - Springer
The causes of many complex human diseases are still largely unknown. Genetics plays an
important role in uncovering the molecular mechanisms of complex human diseases. A key …
important role in uncovering the molecular mechanisms of complex human diseases. A key …
A safety analysis of programmed death 1 pathway inhibitors in patients with solid tumor malignancies and preexisting autoimmune disease
JP Higgins, AV Trinh, ML Watson… - JCR: Journal of …, 2022 - journals.lww.com
Objective The aim of this study was to characterize the safety of programmed death 1
inhibitors in patients with preexisting autoimmune disease. Methods A medical records …
inhibitors in patients with preexisting autoimmune disease. Methods A medical records …
Chronic non-bacterial osteomyelitis and immune checkpoint molecules
U Kaya Akca, E Sag, B Aydın, NK Tasdemir… - Clinical …, 2024 - Springer
Objective We aimed to investigate the plasma levels and cell surface expression of two
checkpoint molecules, TIM-3 (T cell immunoglobulin and mucin domain–containing protein …
checkpoint molecules, TIM-3 (T cell immunoglobulin and mucin domain–containing protein …
PD-1 Deficiency in Regulatory T Cells May be Involved in the Pathogenesis of Takayasu's Arteritis
N Gao, T Li, W Cui, L Zhao… - Clinical and Applied …, 2023 - journals.sagepub.com
Objectives This study aims to investigate whether PD-1 expressions are abnormal in
patients with TAK. Methods PD-1 expression was analyzed by flow cytometry. Serum …
patients with TAK. Methods PD-1 expression was analyzed by flow cytometry. Serum …
[HTML][HTML] Programmed death 1 (PD-1) serum level and gene expression in recent onset systemic lupus erythematosus patients
Aim of the work To investigate the potential association of protein programmed death 1 (PD-
1) serum level and its gene expression inrecent onset systemic lupus erythematosus (SLE) …
1) serum level and its gene expression inrecent onset systemic lupus erythematosus (SLE) …