Natural products: A lead for drug discovery and development

B Chopra, AK Dhingra - Phytotherapy Research, 2021 - Wiley Online Library
Natural products are used since ancient times in folklore for the treatment of various
ailments. Plant‐derived products have been recognized for many years as a source of …

Immunomodulatory functional foods and their molecular mechanisms

JH Kim, DH Kim, S Jo, MJ Cho, YR Cho… - … & molecular medicine, 2022 - nature.com
The immune system comprises a complex group of processes that provide defense against
diverse pathogens. These defenses can be divided into innate and adaptive immunity, in …

Immunopathogenesis of osteoarthritis

A Haseeb, TM Haqqi - Clinical immunology, 2013 - Elsevier
Even though osteoarthritis (OA) is mainly considered as a degradative condition of the
articular cartilage, there is increasing body of data demonstrating the involvement of all …

Cancer chemoprevention with dietary phytochemicals

YJ Surh - Nature Reviews Cancer, 2003 - nature.com
Chemoprevention refers to the use of agents to inhibit, reverse or retard tumorigenesis.
Numerous phytochemicals derived from edible plants have been reported to interfere with a …

Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Ginger—an herbal medicinal product with broad anti-inflammatory actions

R Grzanna, L Lindmark, CG Frondoza - Journal of medicinal food, 2005 - liebertpub.com
The anti-inflammatory properties of ginger have been known and valued for centuries.
During the past 25 years, many laboratories have provided scientific support for the long …

NF-κB signaling: multiple angles to target OA

KB Marcu, M Otero, E Olivotto, R Maria Borzi… - Current drug …, 2010 - ingentaconnect.com
In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-
related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

[PDF][PDF] Los flavonoides: propiedades y acciones antioxidantes

S Martínez-Flórez, J González-Gallego… - Nutrición …, 2002 - academia.edu
Los flavonoides son compuestos fenólicos constituyentes de la parte no energética de la
dieta humana. Se encuentran en vegetales, semillas, frutas y en bebidas como vino y …

[HTML][HTML] Silybin and the liver: from basic research to clinical practice

C Loguercio, D Festi - World journal of gastroenterology: WJG, 2011 - ncbi.nlm.nih.gov
Herbal products are increasingly used, mainly in chronic liver disease. Extracts of milk
thistle, Silymarin and silybin, are the most prescribed natural compounds, with different …

[HTML][HTML] NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis

JA Roman-Blas, SA Jimenez - Osteoarthritis and cartilage, 2006 - Elsevier
The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the
regulation of expression of numerous genes in the setting of the inflammatory response …