[HTML][HTML] Applied machine learning as a driver for polymeric biomaterials design
SM McDonald, EK Augustine, Q Lanners… - Nature …, 2023 - nature.com
Polymers are ubiquitous to almost every aspect of modern society and their use in medical
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …
Molecular bases for temperature sensitivity in supramolecular assemblies and their applications as thermoresponsive soft materials
H Liu, T Prachyathipsakul, TM Koyasseril-Yehiya… - Materials …, 2022 - pubs.rsc.org
Thermoresponsive supramolecular assemblies have been extensively explored in diverse
formats, from injectable hydrogels to nanoscale carriers, for a variety of applications …
formats, from injectable hydrogels to nanoscale carriers, for a variety of applications …
Materials design of highly branched bottlebrush polymers at the intersection of modeling, synthesis, processing, and characterization
Highly branched “bottlebrush” polymers are a class of macromolecules characterized by
side chains that are densely grafted from a backbone that is typically linear. Their unique …
side chains that are densely grafted from a backbone that is typically linear. Their unique …
Cationic bottlebrush polymers outperform linear polycation analogues for pDNA delivery and gene expression
Cationic polymer vehicles have emerged as promising platforms for nucleic acid delivery
because of their scalability, biocompatibility, and chemical versatility. Advancements in …
because of their scalability, biocompatibility, and chemical versatility. Advancements in …
Divergent synthesis of graft and branched copolymers through spatially controlled photopolymerization in flow reactors
In this work, we demonstrate the controlled synthesis of graft and branched copolymers
using one-pot (batch) or one-pass (flow) processes without intermediate purification. The …
using one-pot (batch) or one-pass (flow) processes without intermediate purification. The …
Structural engineering of star block biodegradable polymer unimolecular micelles for drug delivery in cancer cells
The present investigation reports the structural engineering of biodegradable star block
polycaprolactone (PCL) to tailor-make aggregated micelles and unimolecular micelles to …
polycaprolactone (PCL) to tailor-make aggregated micelles and unimolecular micelles to …
From macromonomers to bottlebrush copolymers with sequence control: synthesis, properties, and applications
Bottlebrush polymers (BBPs) are a type of comb-like macromolecule with densely grafted
polymeric sidechains attached to the polymer backbones, and many intriguing properties …
polymeric sidechains attached to the polymer backbones, and many intriguing properties …
Tuning the hydrophilic–hydrophobic balance of molecular polymer bottlebrushes enhances their tumor homing properties
P Ramamurthi, Z Zhao, E Burke… - Advanced …, 2022 - Wiley Online Library
Nanoparticle (NP)‐based drug delivery systems are promising in anticancer therapy,
capable of delivering cargo with superior selectivity and achieving enhanced tumor …
capable of delivering cargo with superior selectivity and achieving enhanced tumor …
Experimental validation on average conformation of a comblike polystyrene library in dilute solutions: universal scaling laws and abnormal SEC elution behavior
X Pan, M Ding, L Li - Macromolecules, 2021 - ACS Publications
In this work, a sample library of well-defined comblike polystyrenes (PS) has been prepared
for the study of average conformation in dilute solutions. The dependences of radius of …
for the study of average conformation in dilute solutions. The dependences of radius of …
[HTML][HTML] Water-soluble polyphosphonate-based bottlebrush copolymers via aqueous ring-opening metathesis polymerization
Ring-opening metathesis polymerization (ROMP) is a versatile method for synthesizing
complex macromolecules from various functional monomers. In this work, we report the …
complex macromolecules from various functional monomers. In this work, we report the …