[HTML][HTML] New developments in the genetics, pathogenesis, and therapy of IgA nephropathy

R Magistroni, VD D'Agati, GB Appel, K Kiryluk - Kidney international, 2015 - Elsevier
Recent years have brought notable progress in the field of IgA nephropathy. Here, we
highlight important new directions and latest developments, including successful discovery …

The mucosa–kidney axis in IgA nephropathy

J Floege, J Feehally - Nature Reviews Nephrology, 2016 - nature.com
Abstract Links between IgA nephropathy (IgAN) and the mucosa have been recognized
since the 1970s. In particular, the observation of visible haematuria induced by respiratory …

Elevated levels of miR‐146a and miR‐155 in kidney biopsy and urine from patients with IgA nephropathy

G Wang, BCH Kwan, FMM Lai, KM Chow… - Disease …, 2011 - Wiley Online Library
Background: Previous studies suggested miR‐146a and miR‐155 play important roles in
innate and adaptive immune responses. We studied intra‐renal and urinary levels of miR …

Pathogenesis of immunoglobulin A nephropathy: recent insight from genetic studies

K Kiryluk, J Novak, AG Gharavi - Annual review of medicine, 2013 - annualreviews.org
Recent genome-wide association studies (GWAS) have identified multiple susceptibility loci
for immunoglobulin A nephropathy (IgAN), the most common form of glomerulonephritis …

Exaggerated systemic antibody response to mucosal Helicobacter pylori infection in IgA nephropathy

J Barratt, EM Bailey, KS Buck, J Mailley… - American journal of …, 1999 - Elsevier
Numerous studies in the literature report aberrant immune responsiveness in
immunoglobulin A (IgA) nephropathy. However, all these studies investigate immune …

Deficient IgA1 immune response to nasal cholera toxin subunit B in primary IgA nephropathy

JW De Fijter, JW Eijgenraam, CA Braam, J Holmgren… - Kidney international, 1996 - Elsevier
Deficient IgA1 immune response to nasal cholera toxin subunit B in primary IgA
nephropathy. Twelve IgA nephropathy (IgAN) patients and 18 controls were immunized with …

The role of secretory IgA and complement in IgA nephropathy

BD Oortwijn, JW Eijgenraam, MP Rastaldi, A Roos… - Seminars in …, 2008 - Elsevier
Immunoglobulin A nephropathy (IgAN) is characterized by glomerular deposition of IgA,
often together with complement components. This deposited IgA is mainly polymeric in …

Secretory immunoglobulin A (IgA) responses in IgA nephropathy patients after mucosal immunization, as part of a polymeric IgA response

JW Eijgenraam, BD Oortwijn… - Clinical & …, 2008 - academic.oup.com
Secretory immunoglobulin A (SIgA), although generated at mucosal surfaces, is also found
in low concentrations in the circulation. Recently, SIgA was demonstrated in mesangial …

Hematuria macroscópica tras inmunización con toxoide tetánico en un paciente con nefropatía IgA

AR García, JF NAVARRO, E GALLEGO - Nefrología, 2002 - revistanefrologia.com
NEFROLOGÍA. Vol. XXII. Número 2. 2002 Hematuria macroscópica tras inmunización con
toxoide tetánico en un paciente con nefropatía IgA A. Rodríguez García, E. Gallego y JF …

[引用][C] Abnormalities of mucosal immune system and human disease

W Strober - Clinical Immunology Newsletter, 1992 - Elsevier