Oral cancer is a type of cancer that develops in the mouth and is one of the deadliest
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …

Epidermal growth factor receptor (EGFR) plays a pivotal role in early brain development,
although its expression pattern declines in accordance with the maturation of the active …

This study focused on gemcitabine (GTB) delivery of cationic polymeric nanoparticles to treat
ovarian cancer in order to promote effective localized delivery and drug retention during …

Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …

Cancer is one of the leading causes of death. Globally a huge number of deaths and new
incidences are reported annually. Heterocyclic compounds have been proved to be very …

Abstract Annexin A2 (ANXA2) is widely used as a marker in a variety of tumors. By
regulating multiple signal pathways, ANXA2 promotes the epithelial‐mesenchymal …

Vorolanib (CM082) is a multi-targeted tyrosine kinase receptor inhibitor with a short half-life
and limited tissue accumulation that has been shown to reduce choroidal …

During the past several decades, numerous studies have provided insights into biological
characteristics of cancer cells and identified various hallmarks of cancer acquired in the …

A set of novel N-substituted-2-((4-oxo-3-phenyl-3, 4-dihydroquinazolin-2-yl) thio) acetamide
3–16 were designed and synthesized from 2-mercapto-3-phenylquinazolinone 2. The …

Guhong injection (GHI) can be used for the treatment of ischemic stroke. We investigated the
antiapoptotic activity of GHI, its ability to repair the cerebral microvessels and mitochondria …