Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

The global increase in type 2 diabetes prevalence is well documented, but international
trends in complications of type 2 diabetes are less clear. The available data suggest large …

Background Randomized trials demonstrated a lower risk of cardiovascular (CV) events with
sodium-glucose cotransporter-2 inhibitors (SGLT-2i) in patients with type 2 diabetes (T2D) at …

Importance In China, diabetes prevalence has increased substantially in recent decades,
but there are no reliable estimates of the excess mortality currently associated with diabetes …

Importance Lowering blood pressure (BP) is widely used to reduce vascular risk in
individuals with diabetes. Objective To determine the associations between BP–lowering …

Background Diabetes mellitus is a major cause of death and disability worldwide and is a
strong risk factor for stroke. Whether and to what extent the excess risk of stroke conferred by …

Aims/hypothesis A previous pooled analysis suggested that women with diabetes are at
substantially increased risk of fatal CHD compared with affected men. Additional findings …

There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at
a lower mean body mass index (BMI) compared with those of European descent. At any …

Background Uncertainties persist about the magnitude of associations of diabetes mellitus
and fasting glucose concentration with risk of coronary heart disease and major stroke …

Background: Type 2 diabetes mellitus is associated with an increased risk of hypertension,
and cardiovascular and renal disease, and it has been recommended that management of …