A diagnosis of malignancy affects parents, siblings, and the extended family more directly
than for an adult patient, and for this reason, care for the family unit has been central to …

Wilms tumour is a primarily sporadic disease, with only 1–2% of affected individuals having
a relative with Wilms tumour. However, bilateral Wilms tumours occur in approximately 5% of …

Hintergrund: Bei der Nephroblastomatose (NBL) handelt es sich um eine seltene fakultative
Prä-kanzerose im Kindesalter, die sich nur sehr selten klinisch manifestiert. Noch immer ist …

Los pacientes con síndrome de Beckwith-Wiedemann (SBW) suelen identificarse al nacer
por la presencia de macrosomía, macroglosia y onfalocele o hernia umbilical. Muchos de …

Nephrogenic rests (NRs) vary in their occurrence of up to 40% in Wilms' tumor (WT)
specimens, marking their universal presence in the bilateral WT. Having served as …

Radical nephrectomy (RN) has traditionally been considered the basis of the surgical
treatment of renal tumors in children and adolescents. The majority of the lessons learned …

Abstract Treatment of pediatric renal malignancies has seen dramatic advances in recent
years. Modifications to surgical approach and the tailoring of chemoradiation protocols have …

Advances in our knowledge of pediatric genitourinary tumors are being made at both the
basic science and clinical levels. The molecular mechanisms underlying these pediatric …

Wilms-Tumoren sind hochmaligne embryonale Mischgeschwulste der Nieren und gehören
mit 7% zu den häufigsten soliden Tumoren des Kindesalters, die meist vor dem 5 …