Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses

HA El-Mahdy, AM Mohamadin, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

The pyroptotic role of Caspase-3/GSDME signalling pathway among various cancer: A Review

AA Bhat, R Thapa, O Afzal, N Agrawal… - International journal of …, 2023 - Elsevier
Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC

R Saddawi-Konefka, A O'Farrell, F Faraji… - Nature …, 2022 - nature.com
Despite the promise of immune checkpoint inhibition (ICI), therapeutic responses remain
limited. This raises the possibility that standard of care treatments delivered in concert may …

Enhancing head and neck tumor management with artificial intelligence: Integration and perspectives

NN Zhong, HQ Wang, XY Huang, ZZ Li, LM Cao… - Seminars in Cancer …, 2023 - Elsevier
Head and neck tumors (HNTs) constitute a multifaceted ensemble of pathologies that
primarily involve regions such as the oral cavity, pharynx, and nasal cavity. The intricate …

Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial

NF Saba, CE Steuer, A Ekpenyong, A McCook-Veal… - Nature medicine, 2023 - nature.com
Anti-programmed cell death protein 1 (PD-1) therapy is a standard of care in recurrent
metastatic head and neck squamous cell carcinoma (RMHNSCC). Vascular endothelial …

Combination of phototherapy with immune checkpoint blockade: Theory and practice in cancer

Y Zhao, X Liu, X Liu, J Yu, X Bai, X Wu, X Guo… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint blockade (ICB) therapy has evolved as a revolutionized therapeutic
modality to eradicate tumor cells by releasing the brake of the antitumor immune response …

HaN‐Seg: The head and neck organ‐at‐risk CT and MR segmentation dataset

G Podobnik, P Strojan, P Peterlin, B Ibragimov… - Medical …, 2023 - Wiley Online Library
Purpose For the cancer in the head and neck (HaN), radiotherapy (RT) represents an
important treatment modality. Segmentation of organs‐at‐risk (OARs) is the starting point of …

[HTML][HTML] Advances in nanomaterials for the diagnosis and treatment of head and neck cancers: A review

C Yu, L Li, S Wang, Y Xu, L Wang, Y Huang, A Hieawy… - Bioactive Materials, 2023 - Elsevier
Nanomaterials (NMs) have increasingly been used for the diagnosis and treatment of head
and neck cancers (HNCs) over the past decade. HNCs can easily infiltrate surrounding …

[HTML][HTML] Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis

G Chen, C Gao, S Jiang, Q Cai, R Li, Q Sun… - Journal of Advanced …, 2024 - Elsevier
Introduction Metastasis is an important cause of high mortality and lethality of oral cancer.
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …