Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-
viral vectors have attracted extensive attentions in treating a variety of diseases, such as …

Liposomes are among the most well-documented drug delivery systems in anticancer
therapy owing to their passive targeting capacities besides inherent biocompatibility and …

Lipid nanoparticles (LNPs) are biocompatible drug delivery systems that have found
numerous applications in medicine. Their versatile nature enables the encapsulation and …

Recently, nucleic acid drugs have been considered as promising candidates in treatment of
various diseases, especially cancer. Because of developing resistance to conventional …

Aptamers are a unique class of nucleic acid molecules currently being investigated for
clinical applications. Aptamers are functional single-stranded oligonucleotides able to form …

Cancer is one of the most difficult diseases to be treated in the world. Immunotherapy has
made great strides in cancer treatment in recent years, and several tumor immunotherapy …

Aptamers have emerged in recent years as alternatives to antibodies or small molecules to
interfere with the immune check points by blocking the PD-1/PD-L1 interactions and …

Immunotherapy has transformed cancer care in the last decade. Aptamers are single-
stranded RNA or DNA oligonucleotides having three-dimensional folding structures …

Aptamers are artificial oligonucleotides with excellent molecule-targeting ability. Compared
with monoclonal antibodies, aptamers have the advantages of low cost, no batch effect, and …

Malignant brain tumor at its fourth stage (glioblastoma) is the most dangerous and an
unsolved medical challenge till today. Present therapeutic strategies including chemo …