Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

The neuropeptide calcitonin gene‐related peptide is well established as a key player in the
pathogenesis of migraine. Clinical studies show calcitonin gene‐related peptide levels …

Background Fremanezumab has demonstrated to be effective, safe, and tolerated in the
prevention of episodic or chronic migraine (CM) in randomized, placebo-controlled trials …

Calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated anti-
migraine efficacy. One remaining question is where do these blockers act? We hypothesized …

The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine.
Although migraine can be treated using CGRP antagonists that act peripherally, the relevant …

Association of receptor activity-modifying proteins (RAMP1-3) with the G protein-coupled
receptor (GPCR) calcitonin receptor-like receptor (CLR) enables selective recognition of the …

Migraine is defined as recurrent attack of headache that are commonly unilateral and
accompanied by gastrointestinal and visual disorders. Migraine is more prevalent in females …

Purpose: The purpose of this study was to study the status and association among tear-
soluble factors, corneal dendritic cell density, vitamin D, and signs and symptoms in dry eye …

Calcitonin gene-related peptide (CGRP) is a vasodilator neuropeptide that is expressed in a
subgroup of small neurons in the dorsal root ganglion (DRG), trigeminal, and vagal ganglia …

Migraine is a painful neurological condition characterized by severe pain on one or both
sides of the head. It may be linked to changes in the gut microbiota, which are influenced by …