Assessment of template based protein structure predictions in CASP9

V Mariani, F Kiefer, T Schmidt, J Haas… - Proteins: Structure …, 2011 - Wiley Online Library
Abstract In the Ninth Edition of the Critical Assessment of Techniques for Protein Structure
Prediction (CASP9), 61,665 models submitted by 176 groups were assessed for their …

CAD‐score: a new contact area difference‐based function for evaluation of protein structural models

K Olechnovič, E Kulberkytė… - … : Structure, Function, and …, 2013 - Wiley Online Library
Abstract Evaluation of protein models against the native structure is essential for the
development and benchmarking of protein structure prediction methods. Although a number …

Target classification in the 14th round of the critical assessment of protein structure prediction (CASP14)

LN Kinch, RD Schaeffer… - Proteins: Structure …, 2021 - Wiley Online Library
An evolutionary‐based definition and classification of target evaluation units (EUs) is
presented for the 14th round of the critical assessment of structure prediction (CASP14) …

Evaluation of the template‐based modeling in CASP12

A Kryshtafovych, B Monastyrskyy… - Proteins: Structure …, 2018 - Wiley Online Library
The article describes results of numerical evaluation of CASP12 models submitted on
targets for which structural templates could be identified and for which servers produced …

CASP10 results compared to those of previous CASP experiments

A Kryshtafovych, K Fidelis… - … : Structure, Function, and …, 2014 - Wiley Online Library
We compare results of the community efforts in modeling protein structures in the tenth
CASP experiment, with those in earlier CASPs particularly in CASP5, a decade ago. There …

Evaluation of disorder predictions in CASP9

B Monastyrskyy, K Fidelis, J Moult… - Proteins: Structure …, 2011 - Wiley Online Library
Lack of stable three‐dimensional structure, or intrinsic disorder, is a common phenomenon
in proteins. Naturally, unstructured regions are proven to be essential for carrying function by …

DNdisorder: predicting protein disorder using boosting and deep networks

J Eickholt, J Cheng - BMC bioinformatics, 2013 - Springer
Background A number of proteins contain regions which do not adopt a stable tertiary
structure in their native state. Such regions known as disordered regions have been shown …

Assessment of template‐based protein structure predictions in CASP10

YJ Huang, B Mao, JM Aramini… - … Structure, Function, and …, 2014 - Wiley Online Library
Template‐based modeling (TBM) is a major component of the critical assessment of protein
structure prediction (CASP). In CASP10, some 41,740 predicted models submitted by 150 …

Key aspects of the past 30 years of protein design

GM Meconi, IR Sasselli, V Bianco… - Reports on Progress …, 2022 - iopscience.iop.org
Proteins are the workhorse of life. They are the building infrastructure of living systems; they
are the most efficient molecular machines known, and their enzymatic activity is still …

CASP9 assessment of free modeling target predictions

L Kinch, S Yong Shi, Q Cong, H Cheng… - Proteins: Structure …, 2011 - Wiley Online Library
We present an overview of the ninth round of Critical Assessment of Protein Structure
Prediction (CASP9)“Template free modeling” category (FM). Prediction models were …