Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …

Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Background Cancer is emerging as a major problem globally, as it accounts for the second
cause of death despite medical advances. According to epidemiological and basic studies …

Circadian rhythms and clock gene expressions are regulated by the suprachiasmatic
nucleus in the hypothalamus, and melatonin is produced in the pineal gland. Although the …

Our study aimed to investigate the expression, functional significance, and related
mechanism of long noncoding RNA CRNDE (colorectal neoplasia differentially expressed) …

Chemically induced proximity (CIP) is a powerful tool to study cellular functions. However
with current CIP inducers it is difficult to directly modulate unligandable and endogenous …

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often
observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an …

Targeting PCAF with small inhibitor molecules has emerged as a potential therapeutic
strategy for the treatment of cancer. Recently, L-45 was identified as a potent …

Cell death is intrinsically linked to inflammatory liver disease and cancer development.
Recent genetic studies have suggested that receptor-interacting protein kinase (RIPK) 1 is …

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related mortality worldwide.
Telmisartan (TLM), a BSC class II drug, has been reported to have antiproliferative activity in …